Results 51 to 60 of about 182,030 (268)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Dependence of optimal spacing on applied field in ungated field emitter arrays

AIP Advances, 2015
In ungated field emitter arrays, the field enhancement factor β of each emitter tip is reduced below the value it would have in isolation due to the presence of adjacent emitters, an effect known as shielding or screening. Reducing the distance b between
J. R. Harris, K. L. Jensen, D. A. Shiffler   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Identification and analysis of drivers for carbon regulatory environmental policies implementation in manufacturing supply chain: A zero carbon perspective

Cleaner Logistics and Supply Chain
Manufacturing supply chains (SCs) has received great attention in both academia and industries to improve ecological sustainability and achieve net-zero emissions.
Rahul Solanki, Devika Kannan, Jyoti Dhingra Darbari, P.C Jha   +3 more
doaj   +1 more source

Study on the implementation of NuScale SMR in Doicesti, Romania [PDF]

EPJ Web of Conferences
The ongoing shift toward low-carbon energy production has renewed interest in advanced nuclear technologies, particularly compact reactor designs. Small Modular Reactors (SMRs) build upon the operating experience of conventional nuclear power plants ...
Brașov Radu-Andrei, Necșoiu Alexandru-Florin, Dinu Victor Emanoil, Popa Viorel   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Moringa arborea-Mediated Iron Oxide Nanoparticles, Their Characterization and Their Anti-Cancer Potential on Highly and Weakly Metastatic Human Breast Cancer Cells

Proceedings
Iron oxide nanoparticles stabilized with Moringa arborea were synthesized [...]
Huzaifa Umar, Maryam Rabiu Aliyu
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Optimized nanofluid coolants enhance thermal performance in ruffled fin automotive radiators

Scientific Reports
Nanofluids offer superior heat transfer compared to conventional automotive coolants, with further improvements achievable through particle hybridization and particle shape effects. This study numerically investigates the thermal performance of a ruffled-
Ferdinard Dika Oshionebo, Doga Kavaz, Dilber Uzun Ozsahin, Michael Adedeji, Berna Uzun, Mustafa Dagbasi, Humphrey Adun   +6 more
doaj   +1 more source

Operational Measures For Energy Efficiency In Shipping [PDF]

Journal of Eta Maritime Science, 2015
The aim of this study is to identify potential solutions to improve energy efficiency of the existing ships. To have an Ship Energy Efficiency Management Plan (SEEMP) on board has become mandatory for all ships starting from 1 January 2013.
Emin ÖZTÜRK
doaj