Results 111 to 120 of about 9,641,659 (250)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Operational Risk Management and Implications for Bank’s Economic Capital – a Case Study [PDF]

open access: yes
In this paper we review the actual operational data of an anonymous Central European Bank, using two approaches described in the literature: the loss distribution approach and the extreme value theory (“EVT”).
Radovan Chalupka, Petr Teply
core  

Analysing the accessibility of a selected southern Baltic Sea location with relevance to conducting surveys

open access: yesScientific Reports
The article presents the accessibility conditions for carrying out research work for an exemplary site in the southern Baltic Sea region. The basic parameter of the state of the marine environment was the significant wave height determined at a frequency
Maria Kubacka   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Operation, operative or operational production management

open access: yes, 2009
The integration of determinant functions of value forming chain is solved by the subsystem of operational control of manufacturing. It is based on an operational plan, which represents the com- plex control instrument formed by the closely tied plans ...
Tomek, Gustav, Vávrová, Věra
core  

Repository Strategic Management Business Journal

open access: yes
Strategic Management Business Journal is a forum for researchers in management science, especially in creating the effect of improving organizational performance in human resource management, financial management, and marketing management.
journal, strategic management business
core   +1 more source

Radiologist Reporting and Operational Management for Patients With Suspected COVID-19. [PDF]

open access: yesJ Am Coll Radiol, 2020
Hammer MM   +6 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Total Airport Management (Operational Concept and Logical Architectur) [PDF]

open access: yes, 2006
Airports are seen as constraints to growth in the future air transport system. In the context of a doubling of traffic by 2020, increased investment, development and research will be needed to support continuous improvement in airport throughput ...
Marsden, Alan   +9 more
core  

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