Results 31 to 40 of about 115,536 (214)
On the bands of the Schrödinger operator with a matrix potential
AbstractIn this article, we consider the one‐dimensional Schrödinger operator with a Hermitian periodic matrix potential Q. We investigate the bands and gaps of the spectrum and prove that most of the positive real axis is overlapped by m bands. Moreover, we find a condition on the potential Q for which the number of gaps in the spectrum of is ...
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
On Absolute Nörlund Spaces and Matrix Operators
An absolute Nörlund space \(|N_p^{\theta}|_k\) is introduced as an extension of absolute Cesàro space \(|C_\alpha|_k\). For \(k\geq 1\) the space \(|N_p^{\theta}|_k\) is defined as: \[ |N_p^{\theta}|_k = \Big\{a=(a_\upsilon): \displaystyle\sum_{n=1}^{\infty}\theta_n^{k-1}\Big|\sum_{\upsilon=1}^{n}\Big(\frac{P_{n-\upsilon}}{P_n}-\frac{P_{n-1-\upsilon ...
Hazar, Güllü Canan +1 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
ASIC Framework Simplified and Operationalised - An Operational Matrix for Optimising the Use of Technologies and Innovations in Medical Education. [PDF]
Owolabi J.
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Extension of Operational Matrix Technique for the Solution of Nonlinear System of Caputo Fractional Differential Equations Subjected to Integral Type Boundary Constrains. [PDF]
Khalil H, Khalil M, Hashim I, Agarwal P.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Resonances for matrix Schrödinger operators
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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