Results 51 to 60 of about 119,125 (264)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
پژوهشهای ریاضی, 2020 The main aim of this paper is to apply the Chebyshev polynomials for the solution of the linear Fredholm integro-differential-difference equation of high orders. It is usually difficult to analytically solve this equation.
Babolian, Fatemeh Chitsaz, Ali Davari
doaj
A numerical scheme for constrained optimal control problems [PDF]
International Journal of Industrial Electronics, Control and Optimization, 2019 In this paper, a numerical technique is proposed to solve optimal control problems (OPCs) of Volterra integral equations (VIEs). We apply the linear B-spline polynomials to solve OPCs by VIEs. The B-spline function divides the interval into sub-intervals
Zahra Shabani, Haleh Tajadodi
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
SELFADJOINTNESS OF INTEGRAL AND MATRIX OPERATORS
Journal of the London Mathematical Society, 2006 Criteria for selfadjointness of integral operators, including matrix operators, based on our earlier domination results are established. The range of applicability is elucidated by carefully chosen examples, not covered by previously known criteria.
Cichoń, Dariusz +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
New real-time demand-side management approach for energy management systems
IET Smart Grid, 2019 This study proposes a new demand-side management (DSM) technique, which is characterised by low computational requirements. The proposed technique relies on developing an operational matrix by the device local controller based on the device ...
Wla E. Elamin, Mostafa F. Shaaban
doaj +1 more source
A Polymorphic Register File for matrix operations [PDF]
2010 International Conference on Embedded Computer Systems: Architectures, Modeling and Simulation, 2010 Previous vector architectures divided the available register file space in a fixed number of registers of equal sizes and shapes. We propose a register file organization which allows dynamic creation of a variable number of multidimensional registers of arbitrary sizes referred to as a Polymorphic Register File.
Catalin Bogdan Ciobanu +3 more
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source