Results 61 to 70 of about 2,716,157 (307)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Numerical Solution using Chebyshev Expansion of the Higher-Orders Linear Fredholm Integro-Differential-Difference Equations with Variable Coefficients

پژوهش‌های ریاضی, 2020
The main aim of this paper is to apply the Chebyshev polynomials for the solution of the linear Fredholm integro-differential-difference equation of high orders. It is usually difficult to analytically solve this equation.
Babolian, Fatemeh Chitsaz, Ali Davari
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

SELFADJOINTNESS OF INTEGRAL AND MATRIX OPERATORS

Journal of the London Mathematical Society, 2006
Criteria for selfadjointness of integral operators, including matrix operators, based on our earlier domination results are established. The range of applicability is elucidated by carefully chosen examples, not covered by previously known criteria.
Cichoń, Dariusz, Stochel, Jan, Szafraniec, Franciszek   +2 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Computing the nearest euclidean distance matrix with low embedding dimensions [PDF]

, 2013
Euclidean distance embedding appears in many high-profile applications including wireless sensor network localization, where not all pairwise distances among sensors are known or accurate.
Qi, Hou-Duo, Yuan, Xiaoming, Qi, Hou Duo
core   +1 more source

A numerical scheme for constrained optimal control problems [PDF]

International Journal of Industrial Electronics, Control and Optimization, 2019
In this paper, a numerical technique is proposed to solve optimal control problems (OPCs) of Volterra integral equations (VIEs). We apply the linear B-spline polynomials to solve OPCs by VIEs. The B-spline function divides the interval into sub-intervals
Zahra Shabani, Haleh Tajadodi
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Application of Haddon’s matrix in qualitative research methodology: an experience in burns epidemiology [PDF]

Background: Little has been done to investigate the application of injury specific qualitative research methods in the field of burn injuries. The aim of this study was to use an analytical tool (Haddon’s matrix) through qualitative research methods to ...
عرشی, شهنام, صادقی, همایون, محمدی, رضا, دلجوان, رضا, فولادی, نسرین   +4 more
core   +1 more source