Results 111 to 120 of about 24,074,970 (295)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Ambient and forced vibration tests of a box girder concrete bridge model

, 2011
4th International Operational Modal Analysis Conference, IOMAC 2011 -- 9 May 2011 through 11 May 2011 -- -- 110155In this paper, ambient and forced vibration tests of a box girder laboratory con-crete bridge model are described to obtain experimental ...
Bayraktar, A., Altunisik, A.C., Sevim, B.   +2 more
core  

Structural Health Monitoring of Steel Garage Model with Stochastic Subspace Identification–Covariance Variance Analysis

Buildings
Traditional methods of determining structural dynamic parameters produce destructive and unreliable results. Therefore, in this study, operational modal analysis method, which is a non-destructive and advanced method, was used to determine structural ...
Furkan Günday
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Operational modal analysis from flight test data

, 2013
In the framework of the operational modal analysis (OMA), several approaches have been developed for estimating the modal parameters, i.e., natural frequencies, damping ratios, and mode shapes.
COPPOTELLI, Giuliano, D. Tozzi, GRAPPASONNI, CHIARA   +2 more
core  

Distributed dynamics approximation through lumping and fuzzy clustering : reliability and validity issues

, 2011
This paper presents a fuzzy reasoning based approach for modeling the distributed dynamics of a parallel flow heat exchanger. Distributed-parameter and lumped-parameter models of the heat exchanger are first derived.
Kidouche, M., Habbi, A.
core   +1 more source

Material Parameters Identification of Historic Lighthouse Based on Operational Modal Analysis. [PDF]

Materials (Basel), 2020
Tomaszewska A, Drozdowska M, Szafrański M.   +2 more
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Operational Modal Analysis, Testing and Modelling of Prefabricated Steel Modules with Different LSF Composite Walls. [PDF]

Materials (Basel), 2020
Rashidi M, Sharafi P, Alembagheri M, Bigdeli A, Samali B.   +4 more
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source