Results 91 to 100 of about 24,074,970 (295)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Modal mass in classical and operational modal analysis

open access: yes, 2019
International Operational Modal Analysis Conference (8th. 2019. Copengahen, Denmark)The financing support given by Banco Santander through the Mobility Grants for Researchers of Professors of the University of Oviedo, is gratefully appreciated.
Brincker, R.   +2 more
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Applications of operational modal analysis to the acoustic of musical instruments: Snare drum and cello

open access: yes, 2019
International Operational Modal Analysis Conference, IOMAC 2019 (8th. 2019. Copengahen, Denmark)The financial support given by the University Institute of Industrial Technology of Asturias (IUTA) through the project SV-17-GIJÓN-1-21 is gratefully ...
Claramunt, R.   +5 more
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Dynamic identification of moumental and historical minaret of the Sehadet

open access: yes, 2015
Modal analysis has been used in three decades in the civil engineering disciplines in order to solve complex structural dynamic problems. In this study, dynamic parameter such as fundamental frequency, mode shapes and damping ratios of minaret of Sehadet
Livaoǧlu, Ramazan   +2 more
core  

Chromaticity Recognition Technology of Colored Noise and Operational Modal Analysis

open access: yesApplied Sciences
Operational Modal Analysis (OMA) refers to the modal analysis with only output vibration signals of a structure in its operating state. Classic OMA has developed multiple recognition methods in both the time and frequency domains, where when the random ...
Xiangyu Lu, Huaihai Chen, Xudong He
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Bayesian oma of offshore rock lighthouses: Surprises with close modes, symmetry and alignment

open access: yes, 2019
A set of seven rock lighthouses around the British Isles was studied by a combination of forced and ambient vibration tests executed with some extreme logistical constraints.
Au, Siu Kui (author)   +5 more
core  

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