Results 71 to 80 of about 24,074,970 (295)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Identification of the modal masses of an UAV structure in operational environment

, 2015
In the framework of Operational Modal Analysis, several methods have been developed to estimate the modal parameters, that is natural frequencies, damping ratios, and mode shapes of a structure in its operative conditions.
Arras, M., Coppotelli, G., Cardinale, M. S.   +2 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Operational modal Analysis of the “Guglia Maggiore” of the “Duomo” in Milano

, 2011
Every city has its own symbol, its very heart. In Milano this symbol, with its six centuries of history, is the Duomo. One of the most impressive buildings in Italy, this unique Gothic cathedral continues to awe citizens and travelers with its timeless ...
VANALI, MARCELLO, G. Busca, CAPPELLINI, ANNA MARIA CHIARA, A. Cappellini, CIGADA, ALFREDO, BUSCA, GIORGIO, A. Cigada   +6 more
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Operational modal testing of an arch type steel highway bridge using SSI technique

, 2011
4th International Operational Modal Analysis Conference, IOMAC 2011 -- 9 May 2011 through 11 May 2011 -- -- 110155The paper determines the dynamic characteristics of an arch type steel highway bridge applying ambient vibration testing.
Bayraktar, A., Altunişik, A.C., Sevim, B.   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Monitoring and Diagnostics of Bridges Using Operational Modal Analysis

Civil and Environmental Engineering
The aging and progressive deterioration of prestressed concrete bridges in the Czech Republic highlight the need for advanced monitoring methods of key structural parameters.
Klusáček Ladislav, Nečas Radim, Koláček Jan, Vašinová Martina, Bezručová Kristína   +4 more
doaj   +1 more source

A Novel method based on operational modal analysis for monitoring the preload degradation of linear guideways in machine tools

Mechanical Engineering Journal, 2017
A novel method for automatically monitoring the preload degradation of linear guideway type (LGT) recirculating linear ball bearings of an X-Y table is proposed.
Ping Chun TSAI, Chih Chun CHENG, Yin Chun CHENG   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source