Results 81 to 90 of about 22,986,797 (251)
Modal parameter extraction via the Loewner Framework: Current progress and future directions [PDF]
Frequency-domain data continues to be widely employed in modal analysis, primarily due to its simplicity and intuitive interpretation. In particular, for simpler systems, an experienced practicioner can often directly discern system modes from frequency ...
Dessena, Gabriele, Civera, Marco
core +3 more sources
, 2011 This paper presents a fuzzy reasoning based approach for modeling the distributed dynamics of a parallel flow heat exchanger. Distributed-parameter and lumped-parameter models of the heat exchanger are first derived.
Kidouche, M., Habbi, A.
core +1 more source
Structural Operativity Evaluation of Strategic Buildings Through Finite Element (FE) Models Validated by Operational Modal Analysis (OMA). [PDF]
Sensors (Basel), 2020 Foti D +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
An integrated permanent dynamic monitoring system of a tall building in central Italy
, 2019 This paper presents results of the dynamic monitoring of a 10-storey r.c. tower in central Italy, focusing on the effects of ambient conditions. The installed monitoring system consists of a set of three accelerometers located on the last floor of the ...
Marco Regni +3 more
core
Optimal sensor placement for the dynamic monitoring of a historical masonry church in central Italy
, 2022 Italy is a seismic prone country with a great heritage of churches and historic masonry buildings that often suffer damage due to earthquakes. For buildings of high cultural value, the damaged structural systems are usually secured through immediate ...
Nicoletti V. +3 more
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Using neural networks for F.E. model updating of structures in operational conditions
, 2015 In this paper, a finite element model updating method based on neural networks is presented. The main objective of the paper is to identify the dynamic properties of a structure from response data recorded during operating conditions, extending the use ...
Arras, M. +2 more
core