Results 81 to 90 of about 24,074,970 (295)

Experimental and operational modal analysis in support of modal model updating - a test case

open access: yes, 2019
The introduction of new equipment on board of aircraft requires fatigue evaluations to determine maintenance intervals. This is particularly true when complex assemblies are required to be installed in aircraft areas exposed to combined stresses, most ...
Coppotelli Giuliano   +1 more
core  

Operational modal analysis with uncertainty quantification for SDDLV-based damage localization

open access: yesMATEC Web of Conferences, 2015
The Stochastic Dynamic Damage Locating Vector (SDDLV) approach is a vibration-based damage localization method based on a finite element model of a structure in a reference state and output-only measurements in both reference and damaged states. A stress
Döhler Michael   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

New insights in the modal identification of a monumental structure from long-term seismic structural monitoring

open access: yes, 2015
The paper summarizes the main findings obtained during the development and management of a longterm seismic structural monitoring system installed in a historic monumental church, the Basilica S.
LEPIDI, MARCO   +3 more
core   +3 more sources

Non-Contact Spatial Vibration Measurement of Cable with a Small Sag: OMA Application for Tension Force Estimation

open access: yesApplied Sciences
This paper presents a method for estimating the tensile force in a cable with a small sag (0 ≤ d/L ≤ 1/8) based on analytical calculations and Operational Modal Analysis (OMA) using non-contact displacement sensors.
Wojciech Pakos, Jacek Grosel
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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