Results 101 to 110 of about 3,613,243 (296)
Monitoring excited hydroxyl (OH*) airglow is broadly used for characterizing the state and dynamics of the terrestrial atmosphere. Recently, the existence of excited hydroxyl was confirmed using satellite observations in the Martian atmosphere.
Dmitry S. Shaposhnikov +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Waking the sleeping giant: Maximising the potential of operational risk management for banks
Within the banking sector operational risk is often perceived to be a less important risk than financial risks such as market or credit risk. Such a view is typically reinforced by the observation that banks are in the business of taking these financial ...
Thirlwell, John +2 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Offshore infrastructure operates in harsh environments where timely monitoring, maintenance planning, and safety management are essential for operational reliability.
Abdullah Alsehaimi +5 more
doaj +1 more source
Unified Digital Twin Approach for Energy Grid Condition and Cybersecurity Monitoring
As renewable energy technologies continue to advance, there are two primary threats to renewable energy assets: physical system failures and cybersecurity threats.
Josh Murray +9 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Environmental monitoring in heterogeneous soil-landscapes; A Dutch case study [PDF]
The spatial heterogeneity of agricultural soil-landscapes is mostly not taken into account in environmental policies. Most environmental goals have been defined at national level or farm level but not at the landscape level.
Kros, J. +4 more
core

