Results 231 to 240 of about 10,006,314 (254)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Operational Research Policy Framework

, 2010
Operational Research Unit, OCB Luxembourg
core  

The Impact of Lean Methods and Tools on the Operational Performance of Manufacturing Organisations [PDF]

International Journal of Production Research, 2014
Evidence suggests that lean methods and tools have helped manufacturing organisations to improve their operations and processes. However, the real effect of these methods and tools on contemporary measures of operational performance, i.e.
Jose Arturo Garza-Reyes, Vikas Kumar
exaly   +2 more sources

Customer Integration and Operational Performance: The Mediating Role of Information Quality [PDF]

Decision Support Systems, 2015
Much supply chain integration literature tends to be biased towards its positive impact on operational performance. However, inconclusive results demand investigation of the mechanisms through which supply chain integration can lead to superior ...
Roberto Chavez, Brian Fynes, Wantao Yu
exaly   +2 more sources

The Complementary Effect of Lean Manufacturing and Digitalisation on Operational Performance

International Journal of Production Research, 2021
Sven-Vegard Buer, Fabio Sgarbossa, Jan Ola Strandhagen   +2 more
exaly  

Linking Business Model Design and Operational Performance: The Mediating Role of Supply Chain Integration

Industrial Marketing Management, 2021
Along Liu, Jibao Gu, Hefu Liu
exaly  

Evaluation of Economic, Environmental and Operational Performance of the Adoption of Cleaner Production: Survey in Large Textile Industries

Journal of Cleaner Production, 2021
Henrricco Nieves Pujol Tucci, Geraldo C Oliveira Neto   +1 more
exaly  

Green Practices and Operational Performance: The Moderating Role of Agility

Journal of Cleaner Production, 2022
Pietro de Giovanni, Alessandra Cozzolino
exaly