Results 71 to 80 of about 429,215 (310)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Perceived Motion Sickness and Effects on Performance Following Naval Transportation [PDF]

open access: yes, 2012
The present study focused on the relationship between previous experiences of, and rated susceptibility to, motion sickness and its correlation to subjective measurements and actual performance.
Fredrik Forsman   +10 more
core   +2 more sources

Assessing the Impact of Nigerian Seaports’ Operational Performance on the Construction Sector’s Contribution to GDP

open access: yesCSID Journal of Infrastructure Development
The construction sector in Nigeria relies heavily on imported materials; however, inefficiencies and frequent delays at the seaports have led to increased costs, significantly affecting the sector’s contribution to the nation’s Gross Domestic Product ...
Ismail Gbolahan Dere   +1 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The performance of the Amoeba distributed operating system

open access: yesSoftware: Practice and Experience, 1989
AbstractAmoeba is a capability‐based distributed operating system designed for high‐performance interactions between clients and servers using the well‐known RPC model. The paper starts out by describing the architecture of the Amoeba system, which is typified by specialized components such as workstations, several services, a processor pool, and ...
Robbert van Renesse   +2 more
openaire   +4 more sources

The influence of continuous improvement and clinical practice on emergency department (ED) operational performance [PDF]

open access: yes
Purpose The study tests the relationships between continuous improvement (CI) and clinical practices (CP) with perceived operational performance in Australian and New Zealand (NZ) emergency departments.
Mitreska, Kristina   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Applying performance measures to support informed decision making at an operational level [PDF]

open access: yes, 2013
Performance Measurement Systems (PMS) have commonly been applied to evaluate and reward performances at managerial levels, especially in the context of supply chain management.
Julião, Jorge   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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