Results 81 to 90 of about 247,114 (294)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Sustainable Supply Chain Management Practices (SSCMPS) and environmental performance: A systematic review

open access: yesSustainable Technology and Entrepreneurship
The study sought to determine the influence of Sustainable Supply Chain Management Practices (SSCMPS) on environmental performance. The study undertook a systematic review and content analysis in order to derive valid insights on the relationship between
Ernest Mugoni   +2 more
doaj   +1 more source

Gestão de recursos humanos e desempenho operacional: evidências empíricas Human resource management and operational performance: empirical evidence

open access: yesGestão & Produção, 2012
A gestão de recursos humanos é frequentemente apontada como uma variável que influencia positivamente no desempenho das organizações. Enquanto argumentos e proposições teóricas de teor similar se multiplicam na literatura especializada, ainda são raras ...
Charbel José Chiappetta Jabbour   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Cultural Diversity and the Operational Performance of Airport Security Checkpoints: An Analysis of Energy Consumption and Passenger Flow

open access: yesEnergies
This paper examines the operational consequences and energy demands associated with the growing cultural diversity of air travellers at airport security checkpoints.
Jacek Ryczyński   +3 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

UNC Charlotte Autonomous Shuttle Pilot Study: An Assessment of Operational Performance, Reliability, and Challenges

open access: yesMachines
This paper presents the findings from an autonomous shuttle pilot program conducted at the University of North Carolina at Charlotte between June and December 2023 as part of the North Carolina Department of Transportation’s Connected Autonomous Shuttle ...
Mohammadnavid Golchin   +4 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

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