Results 111 to 120 of about 2,531,355 (284)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Towards a Swiss National Research Infrastructure

, 2013
In this position paper we describe the current status and plans for a Swiss National Research Infrastructure. Swiss academic and research institutions are very autonomous.
Bohnert, Thomas, Edmonds, Andrew, Eurich, Markus, Flanders, Dean, Flury, Placi, Haug, Sigve, Jamakovic-Kapic, Almerina, Kunszt, Peter, Leinen, Simon, Maffioletti, Sergio, Schiller, Eryk, Stockinger, Heinz   +11 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Evaluating the Latent Tuberculosis Diagnostic Tests Using Fuzzy PROMETHEE: A Multi-Criteria Decision Approach

Cyprus Journal of Medical Sciences
BACKGROUND/AIMS: Latent tuberculosis infection (LTBI) remains a critical challenge in global tuberculosis (TB) control efforts, necessitating effective diagnostic techniques.
Declan Emegano, Nazife Sultanoğlu, Efe Precious Onakpojeruo, Berna Uzun, Dilber Uzun Ozsahin, Tamer Şanlıdağ   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Enhancing tuberculosis vaccine development: a deconvolution neural network approach for multi-epitope prediction

Scientific Reports
Tuberculosis (TB) a disease caused by Mycobacterium tuberculosis (Mtb) poses a significant threat to human life, and current BCG vaccinations only provide sporadic protection, therefore there is a need for developing efficient vaccines.
Auwalu Saleh Mubarak, Zubaida Said Ameen, Abdurrahman Shuaibu Hassan, Dilber Uzun Ozsahin   +3 more
doaj   +1 more source

Operational research training: the course and beyond [PDF]

, 2012
Bissell, K, Edginton, M, Enarson, D A, Harries, A D, Hinderaker, S G, Reid, A J, Satyanarayana, S, Zachariah, R   +7 more
core   +2 more sources

Technical Workshop: Advanced Helicopter Cockpit Design [PDF]

Information processing demands on both civilian and military aircrews have increased enormously as rotorcraft have come to be used for adverse weather, day/night, and remote area missions.
Callas, G. P., Hemingway, J. C.
core   +1 more source

Operational and Research Musculoskeletal Summit: Summit Recommendations [PDF]

, 2006
The Medical Informatics and Health Care Systems group in the Office of Space Medicine at NASA Johnson Space Center (JSC) has been tasked by NASA with improving overall medical care on the International Space Station (ISS) and providing insights for ...
Davis-Street, Janis, Griffin, DeVon, Scheuring, Richard A., Smaka, Todd J., Walton, Marlei   +4 more
core   +1 more source