Results 131 to 140 of about 2,142,897 (254)
Lightweight Data Integration Frameworks for Clinical Research [PDF]
, 2012 Research data from a single clinical study is often spread across multiple applications and systems. We present a reusable, lightweight, secure framework for automatically integrating and querying study data from heterogeneous sources in order to answer ...
Brinkley, James +2 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
A study to guide research and development toward an operational meteorological sounding rocket system Final report, Oct. 1966 - Apr. 1967 [PDF]
Research and development guide for operational meteorological sounding rocket system stressing ...
Atmore, R. F., Billings, R. G.
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Applied Mathematics in Science and EngineeringThe Inertial Tseng Algorithm (ITA) and the Fast Iterative Shrinkage-Thresholding Algorithm (FISTA) are well-established methods that provide effective ways to approximate zeros of the sum of monotone operators.
Abubakar Adamu +3 more
doaj +1 more source
Determinants of Informal Coordination in Networked Supply Chains [PDF]
Purpose – Provide insight into the determinants or constructs that enable informally networked supply chains to operate in order to achieve improved operational performance. Design/methodology/approach – The research is based on a wide literature review,
Ashayeri, J., Ogulin, R., Selen, W.
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Scientific ReportsDespite the strides made in medical science, pancreatic cancer continues to be a threat, highlighting the urgent need for creative strategies to address this concern.
Faisal Abdulaziz Almisned +3 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source