Results 141 to 150 of about 51,144,526 (293)

Operations research in neuroscience [PDF]

Annals of Operations Research, 2017
Erik Kropat, Ruben A. Tikidji-Hamburyan, Gerhard-Wilhelm Weber   +2 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Operational research leading to state-level policy change in tuberculosis undernutrition in Chhattisgarh, India. [PDF]

Public Health Action
Malik C, Gupta V, Shringarpure K, Gupte HA, Keshri VR, Damani M, Shah NN, Sonwani K, Nanda P, Sharma A, Mattoo SK, Shewade HD.   +11 more
europepmc   +1 more source

Use of operational research techniques for concrete mix design: A systematic review. [PDF]

Heliyon, 2023
Rosa AC, Hammad AWA, Boer D, Haddad A.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Improving tuberculosis contact investigation in Chhattisgarh, India: early findings from operational research. [PDF]

Public Health Action
Malik C, Gupta V, Shringarpure K, Gupte HA, Kalkonde Y, Jain Y, Khanna S, Damani M, Shah NN, Sonwani K, Keshri VR, Shewade HD.   +11 more
europepmc   +1 more source

Hand Hygiene Practices and Promotion in Public Hospitals in Western Sierra Leone: Changes Following Operational Research in 2021. [PDF]

Trop Med Infect Dis, 2023
Kamara MN, Lakoh S, Kallon C, Kanu JS, Kamara RZ, Kamara IF, Moiwo MM, Kpagoi SSTK, Adekanmbi O, Manzi M, Fofanah BD, Shewade HD.   +11 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Operational Research on Operational Research: Assessing the Impact of the Structured Operational Research and Training Initiative on Tackling Antimicrobial Resistance in Ghana. [PDF]

Trop Med Infect Dis
Zachariah R, Thekkur P, Braka F, Bruinsma N, Harries AD, Halleux CM, Buabeng KO.   +6 more
europepmc   +1 more source

Operational research to strengthen evidence-based interventions to tackle antimicrobial resistance in the Region of the Americas. [PDF]

Rev Panam Salud Publica, 2023
Celis Y, Esparza G, Zachariah R, Pérez F.   +3 more
europepmc   +1 more source