Results 141 to 150 of about 494,728 (259)

Introduction to the special issue on the role of operational research in future epidemics/ pandemics. [PDF]

Eur J Oper Res, 2023
Farahani RZ, Ruiz R, Van Wassenhove LN.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Routine Immunization Services in The Postpandemic Period: Evidence From Operational Research in Assam. [PDF]

Indian J Community Med
Mahanta TG, Nirmolia N, Mahanta B, Baruah SD, Biswas AB.   +4 more
europepmc   +1 more source

Capacity building in operational research on obstetric fistula: Experience in the Democratic Republic of Congo, 2017-2021. [PDF]

Int J Gynaecol Obstet, 2023
Delamou A, Tripathi V, Camara BS, Sidibe S, Grovogui FM, Kolie D, Bouedouno P, Kourouma K, Banze DF, Mafu MM.   +9 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Is household contact investigation a missing link for tuberculosis care in Chhattisgarh, India?-Operational research using programmatic data. [PDF]

PLOS Glob Public Health
Malik C, Gupta V, Shringarpure K, Gupte HA, Shewade HD, Keshri VR, Tripathi N, Sonwani K, Kalkonde Y, Jain Y.   +9 more
europepmc   +1 more source

Prioritization of operational research questions on COVID-19 vaccination in the African Region. [PDF]

Pan Afr Med J, 2022
Masresha B, Bwaka A, Mihigo R.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Improved Antibiotic Prescribing for Acute Conjunctivitis After Operational Research: A Before-and-After Study in a Ghanaian Eye Hospital. [PDF]

Trop Med Infect Dis
Ansong HK, Nair D, Koomson JA, Amponsah OKO, Acquah JF, Buckman J, Ramsay A, Hope PKF.   +7 more
europepmc   +1 more source

Operational research capacity building through the Structured Operational Research Training Initiative (SORT-IT) in China: implementation, outcomes and challenges. [PDF]

Infect Dis Poverty, 2021
Feng N, Edwards JK, Owiti PO, Zhang GM, Rueda Vallejo ZV, Hann K, Zhou SS, Oo MM, Geoffroy EM, Ma C, Li T, Feng J, Zhang Y, Dong XP.   +13 more
europepmc   +1 more source