Results 181 to 190 of about 51,144,526 (293)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Is household contact investigation a missing link for tuberculosis care in Chhattisgarh, India?-Operational research using programmatic data. [PDF]

PLOS Glob Public Health
Malik C, Gupta V, Shringarpure K, Gupte HA, Shewade HD, Keshri VR, Tripathi N, Sonwani K, Kalkonde Y, Jain Y.   +9 more
europepmc   +1 more source

Capacity building in operational research on obstetric fistula: Experience in the Democratic Republic of Congo, 2017-2021. [PDF]

Int J Gynaecol Obstet, 2023
Delamou A, Tripathi V, Camara BS, Sidibe S, Grovogui FM, Kolie D, Bouedouno P, Kourouma K, Banze DF, Mafu MM.   +9 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

A Qualitative, multitiered operational research model for teenagers and young adults with autism: Actionable insights from an Indian context. [PDF]

Indian J Psychiatry
Chandran S, Shetty H, Mathew A, Rao V, Mysore A.   +4 more
europepmc   +1 more source

Prioritization of operational research questions on COVID-19 vaccination in the African Region. [PDF]

Pan Afr Med J, 2022
Masresha B, Bwaka A, Mihigo R.
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Improved Antibiotic Prescribing for Acute Conjunctivitis After Operational Research: A Before-and-After Study in a Ghanaian Eye Hospital. [PDF]

Trop Med Infect Dis
Ansong HK, Nair D, Koomson JA, Amponsah OKO, Acquah JF, Buckman J, Ramsay A, Hope PKF.   +7 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Advancing implementation science and policy on HIV/AIDS: outcomes from the fourth edition of the Cameroon HIV operational research forum (CAM-HERO) 2024. [PDF]

Pan Afr Med J
Mabou GT, Ebasone PV, Sam-Agudu NA, Tchendjou P, Adirieje C, Tchounga B, Ndom MS, Fokam J, Ajeh R, Khan EM, Shu EN, Katayi ET, Atanga PN, Ngamani ML, Lengouh C, Nekame LG, Djikeussi T, Tene G, Chenwi C, Semengue ENJ, Chiabi E, Nasah J, Ching J, Ngo-Malabo E, Nshom E, Meka AFZ, Tchakounte BY, Ayima CW, Tumasang F, Kana R, Nka AD, Ndongo FA, Tabala FN, Noah YA, Ndie J, Ngu PN, Ketchaji A, Talla S, Edakedi MR, Banboye R, Nzeusseu HK, Ngonga L, Muffih PT, Bisseck ACZ, Dzudie A.   +44 more
europepmc   +1 more source