Results 101 to 110 of about 312,703 (305)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Operational risk and the three lines of defence in the UK financial institutions: Is three really the magic number? [PDF]

open access: yes, 2017
There has been growing interest in the need for financial services firms to develop and implement robust systems and structures for managing operational risk.
Ring, P.   +7 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Risk and the Republican National Convention: Application of the Novel COVID-19 Operational Risk Assessment. [PDF]

open access: yesDisaster Med Public Health Prep, 2022
Callaway D   +6 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

BUSINESS ETHICS AND OPERATIONAL RISK MANAGEMENT IN MALAYSIAN LOCAL CONVENTIONAL BANKS

open access: yesStudia Universitatis Babeş-Bolyai Negotia, 2016
Purpose: This is a conceptual paper that discusses on the importance of business ethics and operational risk management in banks. Design/methodology/approach: The paper review the literatures of business ethics and operational risk management in banks.
Noor Fareen ABDUL RAHIM, Hazlinda HASSAN
doaj   +2 more sources

Operational risk, omissions and liability in policing [PDF]

open access: yes, 2018
Recent decades have seen the sensitisation of UK society towards harm and policing ‘failures’ become increasingly significant. This paper is intended to stimulate thought and debate by analysing some consequences of these developments.
Bryant, R., Heaton, R., Tong, S.
core  

Capital assessment of operational risk for the solvency of health insurance companies

open access: yes, 2012
Solvency II rules are expected to generate a system in which improved risk management, including management of operational risk, is provided to insurers through a lower charge of solvency capital.
Martínez Torre-Enciso, María Isabel   +1 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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