Results 141 to 150 of about 260,204 (258)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Autochthonous tick-borne encephalitis virus (TBEV) - seropositive cattle in Belgium: a risk-based targeted serological survey

Parasites & Vectors, 2014
S Roelandt, V Suin, F Riocreux, S Lamoral, S Van der Heyden, Y Van der Stede, B Lambrecht, B Cay, B Brochier, S Roels, S Van Gucht   +10 more
doaj   +1 more source

Integrating GIS and local knowledge for optimised medical supply prepositioning in flood-prone Nigeria: a strategic framework. [PDF]

Glob Health Action
Massironi M, Jimoh M, Ogah J, Kolawole OM, Bounds M.   +4 more
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Mining corridors as emergence interfaces: an evidence-informed one health operational framework for prevention of infectious disease outbreaks in Kédougou, Senegal. [PDF]

Front Public Health
Sow B, Sadio BD, Diarra M, Gaye A, Ndione MHD, Diallo D, Moukaha Doukanda SF, Sankhe S, Faye O, Dia N, Talla C, Faye O, Loucoubar C, Fall G, Diallo B, Sow A, Fall IS, Diallo M, Barry MA, Diagne MM.   +19 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Risk determination for non-target arthropods from outdoor space applications of mosquito adulticides. [PDF]

J Med Entomol
Peterson RKD, Kennedy TE, Strand JR.
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Healthcare-associated transmission and early IPC system vulnerabilities during the 2026 Bundibugyo Ebola outbreak in eastern Democratic Republic of the Congo. [PDF]

Antimicrob Resist Infect Control
Bepouka B, Kafua M.
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source