Results 161 to 170 of about 9,466,795 (394)
On the selection of loss severity distributions to model operational risk [PDF]
, 2019 Daniel Hadley, Harry Joe, Natalia Nolde
openalex +1 more source
Operational Risk Management using a Fuzzy Logic Inference System [PDF]
Operational Risk (OR) results from endogenous and exogenous risk factors, as diverse and complex to assess as human resources and technology, which may not be properly measured using traditional quantitative approaches.
Alejandro Reveiz, Carlos León
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Theoretical Sensitivity Analysis for Quantitative Operational Risk Management
, 2011 Takashi Kato
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
CAPITAL REQUIREMENTS FOR OPERATIONAL RISK: AN INCENTIVE APPROACH [PDF]
This paper proposes a simple continuous time model to analyze capital charges for operational risk. We find that undercapitalized banks have less incentives to reduce their operational risk exposure.
Mohamed Belhaj
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Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Operational Risk Modelling and Capital Adequacy – are There any Rewards in Greater Complexity? [PDF]
The paper applies the methodologies proposed by Basel Committee on Banking Supervision for assessing the capital requirements in the context of operational risk to a Romanian commercial bank.
Anghelache, Gabriela Victoria +2 more
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