Results 71 to 80 of about 6,759,106 (297)
African Journal on Land Policy and Geospatial SciencesContext and background Fit-for-Purpose Land Administration (FFP-LA) framework provides a pragmatic approach to enhancing tenure security, reducing disputes, and facilitating planned urban development in resource-constrained areas.
Anisher Ann Nakanwagi +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Applied Computer Systems, 2020 Well logging, also known as a geophysical survey, is one of the main components of a nuclear fuel cycle. This survey follows directly after the drilling process, and the operational quality assessment of its results is a very serious problem. Any mistake
Abramov Kirill, Grundspenkis Janis
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Nitrogen and Phosphorous Removal in Municipal Wastewater Treatment Plants in China: A Review
International Journal of Chemical Engineering, 2010 Surface water environment in China was degraded rapidly in the last two decades, resulting in increasingly tighten criteria issued for municipal wastewater treatment plants (WWTPs).
Yong Qiu, Han-chang Shi, Miao He
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
A Framework to Select Techniques Supporting Project Risk Management [PDF]
, 2012 The need for increasing quality while reducing time and costs asks for developing knowledge about how to manage risk in projects. However, communication and knowledge creation are not easy tasks, especially when dealing with uncertainty, because decision-
Grimaldi, Sabrina +5 more
core +1 more source
Application of Operational Research Techniques in the Assessment of Health Information Technology
پژوهشهای سلامتمحور, 2019 Application of Operational Research Techniques in the Assessment of Health Information Technology Bagherian Hossein1*, Forouzandeh Farideh2 1.
Hossein Bagherian, Farideh Forouzandeh
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