Results 81 to 90 of about 6,759,106 (297)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An Aggregated Information Technology Checklist for Operational Risk Management [PDF]
This study addresses the issue of the Information Technology (IT) Governance frameworks and standards that respond to different levels of operational risks, especially those caused by the information systems and technology infrastructure.
Mehmet Zeki Önal
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Operational risk assessment of transmission Systems: A review
International Journal of Electrical Power & Energy SystemsThe deterministic techniques in use for transmission-grid planning and operation have resulted in a high reliability, but they have certain limitations that could be removed by applying stochastic techniques.
Zunaira Nazir, Math Bollen
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
An analysis of the causes of track twist at high speed of driving
Production Engineering Archives, 2019 The research of railway track surfaces is aimed at improving the quality of railway infrastructure and providing the chance of improving the safety of driving. Therefore, it is advisable to constantly monitor track surface, but the research itself is not
Pacana Andrzej, Siwiec Dominika
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Implications of alternative operational risk modeling techniques [PDF]
Quantification of operational risk has received increased attention with the inclusion of an explicit capital charge for operational risk under the new Basle proposal.
Patrick de Fontnouvelle +2 more
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AutomationThis paper presents a comprehensive overview of permanent magnet synchronous motors (PMSMs), including their classifications, applications, and vector control strategies. It explores various control techniques, including maximum torque per ampere (MTPA),
Mahmoud M. Elkholy +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
, 2006 A modal analysis aims at the identification of the modal parameters of a test structure from the measured vibratory behaviour. Traditionally, both the input forces and the resulting responses are measured. However, in many applications it is not possible
Heylen, Ward +3 more
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