Results 141 to 150 of about 2,626,282 (391)
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Peri‐operative management of the obese surgical patient 2015
Anaesthesia, 2015 Guidelines are presented for the organisational and clinical peri‐operative management of anaesthesia and surgery for patients who are obese, along with a summary of the problems that obesity may cause peri‐operatively.
C. Nightingale +14 more
semanticscholar +1 more source
"Co-Operative Identity" - A Theoretical Concept for Dynamic Analysis of Practical Co-Operation: The Dutch Case [PDF]
The "concept of the co-operative identity" (consisting from the definition, aims and functions of cooperatives and the so-termed co-operative principles) serves as a general theoretical background for the economic analysis of agricultural co-operation ...
Szabo, Gabor G.
core +1 more source
Comparison of Visual Analog Pain Score Reported to Physician vs Nurse in Nonoperatively Treated Foot and Ankle Patients [PDF]
, 2019 Background: Patient reported outcome measures (PROMs) are taking a more prominent role in Orthopedics as health care seeks to define treatment outcomes. The Visual Analogue Scale (VAS) is considered a reliable measure of acute pain.
Dewar, BS, Cuyler +4 more
core +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Varicocele and Testicular Pain: A Review
The World Journal of Men's Health, 2019 Varicocele is the dilatation of the scrotal portion of pampiniform plexus and the internal spermatic venous system. About 15% of men suffer from scrotal varicocele and 2% to 10% of them complain of pain.
Sunghyun Paick, Woo Suk Choi
doaj +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Orthopaedic SurgeryObjectives B3GALT6 ‐related disorders are characterized by severe early‐onset spinal deformities requiring surgical corrections but are associated with increased risks of perioperative complications.
Aoran Maheshati +13 more
doaj +1 more source