Symmetry preserving self-adjoint extensions of Schrödinger operators with singular potentials [PDF]
, 2010 Д. М. Гитман +3 more
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RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
THE FORMATION OF THE CONSUMPTION RATE OF SPARE PARTS, MATERIALS AND TOOLS FOR MAINTENANCE AND REPAIR
Научный вестник МГТУ ГА, 2016 While in operation aircraft components are replaced due to the end of their service life or failure. Needs formation of the operator in the replaceable components considerably determines the operating efficiency of the aircraft type and particular ...
S. V. Daletskiy +2 more
doaj
Post-Hopf algebras, relative Rota-Baxter operators and solutions of the Yang-Baxter equation [PDF]
, 2022 Yunnan Li, Yunhe Sheng, Rong Tang
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NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
On differential operators permutable with Lie continuous groups of transformations [PDF]
, 1937 Kôshichi Toyoda
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Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Optimal domain of $q$-concave operators and vector measure representation of $q$-concave Banach lattices [PDF]
, 2015 O. Delgado, Enrique A. Sánchez‐Pérez
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