Results 101 to 110 of about 2,866,909 (331)

Design of the strategy and architecture of different enterprises’ middle platform

open access: yesDianxin kexue, 2020
With the national economic transition and rapid development of technology,enterprises need digital transition.How to accelerate transition through IT architecture upgrading has become a new research topic for enterprises.The definition,function and ...
Yinghui LIU   +4 more
doaj  

On the existence and uniqueness of solution to Volterra equation on a time scale

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
Using a global inversion theorem we investigate properties of the following ...
Kluczyński Bartłomiej
doaj   +1 more source

Operators in Nature, Science, Technology, and Society: Mathematical, Logical, and Philosophical Issues

open access: yesPhilosophies, 2017
The concept of an operator is used in a variety of practical and theoretical areas. Operators, as both conceptual and physical entities, are found throughout the world as subsystems in nature, the human mind, and the manmade world.
Mark Burgin, Joseph Brenner
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Pendampingan Pelatihan Pengoperasian Mesin Potong Rumput Untuk Optimalisasi Panen Rumput Gajah Pada Kelompok Tani Mandiri Rancage Curugrendeng

open access: yesJurnal Abdimas Indonesia
Kelompok Tani Mandiri Rancage Curugrendeng memiliki jumlah anggotanya sebanyak 63 orang dan saat ini berkegiatan dalam usaha budidaya rumput dengan luas kebun mencapai 62 hektar yang tersebar di tiga wilayah yaitu di Subang, Sumedang dan Purwakarta ...
Jaja Jaja   +5 more
doaj   +1 more source

Estimating the spectral gap of a trace-class Markov operator [PDF]

open access: green, 2017
Qian Qin, James P. Hobert, Kshitij Khare
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy