Results 81 to 90 of about 451,808 (267)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Kwartalnik Filmowy, 2001 Esej poświęcony twórczości światowej sławy operatora Vittorio Storaro. Chmielecki analizuje wizualny aspekt Tanga Carlosa Saury. Autor argumentuje, że Storaro reprezentuje postawę, zgodnie z którą rzeczywistość profilmowa okazuje się zbyt uboga, by mogła
Konrad Chmielecki
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Dans les « coulisses » du métier d’opérateur de vidéosurveillance
Criminologie, 2013 Pièces maîtresses des dispositifs de vidéosurveillance mis en place dans nombre de villes françaises aujourd’hui, les opérateurs officiant derrière les écrans demeurent pourtant des acteurs de la sécurité dont on sait peu de chose.
Tanguy Le Goff
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
A relation between two simple Hardy-Mulholland-type inequalities with parameters
Journal of Inequalities and Applications, 2016 By means of weight coefficients and the technique of real analysis, a new Hardy-Mulholland-type inequality with the kernel K λ ( m , n ) : = 1 ln λ U m + ln λ V n + α | ln λ U m − ln λ V n | $$ K_{\lambda}(m,n):=\frac{1}{\ln^{\lambda}U_{m}+\ln^{\lambda ...
Qiang Chen, Yanping Shi, Bicheng Yang
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source