Results 61 to 70 of about 422,561 (267)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Cost-Effective Target Capacity Assessment in the Energy Transition: The Italian Methodology

open access: yesEnergies
Long-term transmission expansion planning has to face the energy transition in a restructured electricity market environment. Increased transmission capacity within and between Member States is likely to play an essential role in maintaining the secure ...
Enrico Maria Carlini   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The West African port system: global insertion and regional particularities

open access: yesEchoGéo, 2012
The changes that occur in a port system depend on how it is integrated within the global maritime network and its relationship with local and regional spaces with their specific economic, political and geographical characteristics.
Jean Debrie
doaj   +1 more source

To operate or not to operate, that is the question

open access: yesBone & Joint Research, 2016
To operate or not to operate, that is the question. In the case of a displaced diaphyseal fracture of the femur, this question is not a challenge. We do not need a randomised controlled trial to determine if intramedullary nailing of a fracture of the femur is more effective, for any outcome ...
Ghert, M., McKee, M.
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

MBI: A Beacon of Hope in Methamphetamine Contamination Remediation

open access: yesJournal of Aboriginal Economic Development
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Clarence Natomagan
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

THE HEAT OPERATOR OF A TRANSVERSALLY ELLIPTIC OPERATOR [PDF]

open access: yesJP Journal of Geometry and Topology, 2017
Let $G$ be a connected compact Lie group. We study the heat operator of a $G$-transversally elliptic operator. After we review the spectral properties of a $G$-transversally elliptic operator, we define the character, that is a distribution on $G$ generalizing the trace of the heat operator to the $G$-equivariant case.
openaire   +2 more sources

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