Results 41 to 50 of about 422,561 (267)
This guidance is designed to assist risk assessors and applicants when quantifying potential non‐dietary, systemic exposures as part of regulatory risk assessment for plant protection products (PPPs). It is based on the Scientific Opinion on ‘Preparation
European Food Safety Authority (EFSA) +9 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Data-Driven Operational Risk Assessment in Renewable-Rich Power System. An Automated Probabilistic Power Flow and SCADA Data Mining Framework [PDF]
The increasing penetration of variable renewable energy (VRE) introduces profound stochastic uncertainties into power systems, rendering traditional deterministic security assessments insufficient.
Nhan Luong Phu +4 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Operator Calculus of Quantized Operator [PDF]
The notational ambiguities in Feynman's calculus are all remedied here by setting a more natural foundation of the ordered exponential operators, which will be called briefly "expansional" operators in this paper. The essential point to be stressed is that the pure exponential opErator is merely a special case of the more wider class of operators, i.e.,
openaire +2 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Digital transformation at the Grand Egyptian Museum
The Grand Egyptian Museum (GEM) represents a transformative addition to Egypt's cultural and heritage landscape, set to redefine the traditional museum experience through immersive, interactive, and technology-driven exhibits.
Nancy Ali +2 more
doaj +1 more source
Abstract In this paper we define a general integral operator for analytic functions in the open unit disk and we determine some conditions for univalence of this integral operator.
Virgil Pescar, Daniel Breaz
openaire +2 more sources

