Results 51 to 60 of about 2,130,795 (350)

Non-operative management of rectal cancer: understanding tumor biology [PDF]

open access: yesMinerva Chirurgica, 2018
The management of locally-advanced rectal cancer involves a combination of chemotherapy, chemoradiation, and surgical resection to provide excellent local tumor control and overall survival. However, aspects of this multimodality approach are associated with significant morbidity and long-term sequelae.
Iris H Wei, Julio Garcia-Aguilar
openaire   +3 more sources

Schauder a priori estimates and regularity of solutions to boundary-degenerate elliptic linear second-order partial differential equations [PDF]

open access: yes, 2013
We establish Schauder a priori estimates and regularity for solutions to a class of boundary-degenerate elliptic linear second-order partial differential equations.
Camelia Pop   +3 more
core   +2 more sources

On ξ(s)-Quadratic Stochastic Operators on Two-Dimensional Simplex and Their Behavior

open access: yesAbstract and Applied Analysis, 2013
A quadratic stochastic operator (in short QSO) is usually used to present the time evolution of differing species in biology. Some quadratic stochastic operators have been studied by Lotka and Volterra.
Farrukh Mukhamedov   +2 more
doaj   +1 more source

Development and Validation of a Novel Prognostic Model for Acute Myeloid Leukemia Based on Immune-Related Genes

open access: yesFrontiers in Immunology, 2021
The prognosis of acute myeloid leukemia (AML) is closely related to immune response changes. Further exploration of the pathobiology of AML focusing on immune-related genes would contribute to the development of more advanced evaluation and treatment ...
Ran Li   +11 more
doaj   +1 more source

Optimal reporter placement in sparsely measured genetic networks using the Koopman operator [PDF]

open access: yesIEEE Conference on Decision and Control, 2019
Optimal sensor placement is an important yet unsolved problem in control theory. In biological organisms, genetic activity is often highly nonlinear, making it difficult to design libraries of promoters to act as reporters of the cell state.
A. Hasnain, N. Boddupalli, Enoch Yeung
semanticscholar   +1 more source

Wnt pathway-related three-mRNA clinical outcome signature in bladder urothelial carcinoma: computational biology and experimental analyses

open access: yesJournal of Translational Medicine, 2021
Background The Wnt signaling pathway is core to the growth of bladder tumors. Epithelial-to-mesenchymal transition (EMT) is significant for bladder tumor metastasis.
Siqing Sun   +3 more
semanticscholar   +1 more source

Shaping Pulses to Control Bistable Monotone Systems Using Koopman Operator [PDF]

open access: yes, 2016
In this paper, we further develop a recently proposed control method to switch a bistable system between its steady states using temporal pulses. The motivation for using pulses comes from biomedical and biological applications (e.g.
Goncalves, Jorge   +2 more
core   +2 more sources

Recent Advances in Operations Research in Computational Biology, Bioinformatics and Medicine [PDF]

open access: yesRAIRO - Operations Research, 2016
The EURO Working Group on Operations Research in Computational Biology, Bioinformatics and Medicine held its fourth conference in Poznan-Biedrusko, Poland, June 26–28, 2014. The editorial board of RAIRO-OR invited submissions of papers to a special issue on Recent Advances in Operations Research in Computational Biology, Bioinformatics and Medicine ...
Metin Turkay   +3 more
openaire   +4 more sources

A homotopy perturbation method with Elzaki transformation for solving the fractional Biswas–Milovic model

open access: yesOpen Physics, 2023
In this research, we use the homotopy perturbation method (HPM) combined with the Elzaki transform to investigate the fractional Biswas–Milovic equation (BME) within the framework of the Caputo operator.
Alshehry Azzh Saad   +2 more
doaj   +1 more source

Modular organisation of interaction networks based on asymptotic dynamics [PDF]

open access: yes, 2012
This paper investigates questions related to the modularity in discrete models of biological interaction networks. We develop a theoretical framework based on the analysis of their asymptotic dynamics.
Delaplace, Franck   +3 more
core   +6 more sources

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