Results 81 to 90 of about 1,286,443 (317)

On ( p , q ) $(p,q)$ -Szász-Mirakyan operators and their approximation properties

Journal of Inequalities and Applications, 2017
In the present paper, we introduce a new modification of Szász-Mirakyan operators based on ( p , q ) $(p, q)$ -integers and investigate their approximation properties. We obtain weighted approximation and Voronovskaya-type theorem for new operators.
M Mursaleen, AAH Al-Abied, Abdullah Alotaibi   +2 more
doaj   +1 more source

Towards a theory of operational excellence [PDF]

Total Quality Management & Business Excellence, 2018
The term Operational Excellence is widely applied to businesses but the meaning is ill-defined and is often used as a desired goal. This paper provides a comprehensive review of Operational Excellence and starts to address the criticism of its lack of theoretical foundation.
Found, Pauline, Lahy, Andrew, Williams, Sharon J., Hu, Qing, Mason, Robert   +4 more
openaire   +4 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Bézier-Summation-Integral-Type Operators That Include Pólya–Eggenberger Distribution

Mathematics, 2022
We define the summation-integral-type operators involving the ideas of Pólya–Eggenberger distribution and Bézier basis functions, and study some of their basic approximation properties. In addition, by means of the Ditzian–Totik modulus of smoothness, we
Syed Abdul Mohiuddine, Arun Kajla, Abdullah Alotaibi   +2 more
doaj   +1 more source

Operator Methods in Approximation Theory [PDF]

Journal of Function Spaces, 2019
n ...
Vita Leonessa, Tuncer Acar, Mirella Cappelletti Montano, Pedro Garrancho   +3 more
openaire   +5 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Homotopy Operators and Identity-Based Solutions in Cubic Superstring Field Theory

, 2011
We construct a class of nilpotent operators using the BRST current and ghost fields in superstring theory. The operator can be realized in cubic superstring field theory as a kinetic operator in the background of an identity-based solution.
Inatomi, Shoko, Kishimoto, Isao, Takahashi, Tomohiko   +2 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

On Kantorovich modification of ( p , q ) $( p,q ) $ -Baskakov operators

Journal of Inequalities and Applications, 2016
The concern of this paper is to introduce a Kantorovich modification of ( p , q ) $( p,q ) $ -Baskakov operators and investigate their approximation behaviors. We first define a new ( p , q ) $( p,q ) $ -integral and construct the operators.
Tuncer Acar, Ali Aral, Syed Abdul Mohiuddine   +2 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source