Results 101 to 110 of about 736,346 (302)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Twelfth Illinois Custom Spray Operators' Training School: summaries of presentations [PDF]
Made available in DSpace on 2016-03-17T21:24:35Z (GMT). No. of bitstreams: 2 7912186_1960.pdf: 6656063 bytes, checksum: e47c87ab276935617d175d987977d22d (MD5) license.txt: 4846 bytes, checksum: 927d59ba442de31571446841df3d90ca (MD5) Previous issue date:
Illinois Custom Spray Operators' School
core
Unbounded B-Fredholm operators on Hilbert spaces [PDF]
This paper is concerned with the study of a class of closed linear operators densely defined on a Hilbert space H and called B-Fredholm operators.
Berkani, M. +3 more
core +1 more source
Influence of human factors on Just-in-Time economic success
Just-in-time (JIT) has several critical success factors (CSF), including human resources. This study reports a structural equation model (SEM) and a sensitivity analysis that relates some of them, such as managerial commitment (MAC), operators (OPE ...
Jorge Luis García Alcaraz +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Sixteenth Illinois Custom Spray Operators' Training School: summaries of presentations [PDF]
Made available in DSpace on 2016-03-17T21:24:37Z (GMT). No. of bitstreams: 2 7912186_1964.pdf: 9025318 bytes, checksum: 0b431ec596ebc4766350ea5536f6558a (MD5) license.txt: 4846 bytes, checksum: 927d59ba442de31571446841df3d90ca (MD5) Previous issue date:
Illinois Custom Spray Operators' School
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Norm and Numerical Radius Inequalities for a Product of Two Linear Operators in Hilbert Spaces [PDF]
The main aim of the present paper is to establish some norm and numerical radius inequalities for the composite operator BA under suitable assumptions for the transform Cα ,β (T) := (T∗ −α I)(β I−T) , where α ,β ∈ C and T ∈ B(H), of the operators ...
S. S. Dragomir +2 more
core +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

