Results 81 to 90 of about 3,216,975 (364)
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
On Unbounded Composition Operators in $L^2$-Spaces
Fundamental properties of unbounded composition operators in $L^2$-spaces are studied. Characterizations of normal and quasinormal composition operators are provided. Formally normal composition operators are shown to be normal.
A Brown +52 more
core +2 more sources
Light-ray operators in conformal field theory [PDF]
A bstractWe argue that every CFT contains light-ray operators labeled by a continuous spin J. When J is a positive integer, light-ray operators become integrals of local operators over a null line.
Petr Kravchuk, D. Simmons-Duffin
semanticscholar +1 more source
Pseudodifferential operators and Hecke operators
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Protein kinase FAM20C—when subcellular localization matters
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Some integral operators of Buschman-Erdélyi type
New integral operators involving the generalized Legendre function Pr-n(z) are introduced. Sorne integrals are evaluated.
N. Virchenco
doaj
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Baxter operators for arbitrary spin
We construct Baxter operators for the homogeneous closed $\mathrm{XXX}$ spin chain with the quantum space carrying infinite or finite dimensional $s\ell_2$ representations.
Baxter +37 more
core +1 more source

