Results 101 to 110 of about 118,304 (234)
LexR1 is a LuxR‐type regulator that links nutrient sensing to effector gene expression in Legionella. Activated by a casamino acid‐derived ligand, LexR1 directly controls multiple effector genes using a conserved regulatory element present in numerous putative effectors across different Legionella species.
Chen Adler, Gil Segal
wiley +1 more source
Low basal activity of divergent promoters driving transcription of the trimethylamine N‐oxide (TMAO) sensor TorT and kinase TorS is integral to an O2‐regulated bet‐hedging strategy for continued E. coli growth upon the onset of anaerobiosis. This, along with repression by IscR, promotes noise in the TorS to TorT ratio, which is critical for adaptation ...
Erin L. Mettert +4 more
wiley +1 more source
A Spontaneous Mutation in tfoX Impairs Bioluminescence in Photobacterium kishitanii ANT‐2200
A frameshift mutation in tfoX generates a truncated regulator associated with reduced lux–rib expression and low luminescence. Complementation with wild‐type tfoX restores transcription and light production, supporting a role for TfoX in regulating bioluminescence independently of quorum sensing.
Capucine Le Cam Ligier +6 more
wiley +1 more source
Metagenomic Evaluation of Oral Microbiota in Patients Affected by Oral Lichen Planus: A Pilot Study
ABSTRACT Objective To characterize the oral bacterial and fungal microbiota of symptomatic oral lichen planus patients undergoing topical corticosteroid therapy and to explore microbial patterns potentially associated with subsequent oral candidiasis. Methods Twelve patients with clinically and histologically confirmed OLP were enrolled.
A. Dormiente +5 more
wiley +1 more source
The ComEA/ComEC Operon is Critical for Nitrosative Stress Tolerance by an Oral Commensal
ABSTRACT Oral commensal streptococci play a large role in mediating microbial homeostasis. Our prior work has demonstrated that hydrogen peroxide (H2O2) produced by oral commensal streptococci can react with salivary nitrite (NO2) and generate peroxynitrite (ONOO−), a potent antimicrobial.
Sara E. Edmonds +3 more
wiley +1 more source
ABSTRACT The single crossover occurring via homologous recombination is a common phenomenon existing among microbes like Escherichia coli, Bacillus subtilis, Vibrio natriegens, Gluconobacter oxydans and most cyanobacteria species, threatening the stability of engineered strains and challenging iterative genetic engineering. Among them, we take the fast‐
Shubin Li +5 more
wiley +1 more source
RNA‐Guided Engineering of the Chloroplast Genome Enabled by Plastid‐Expressed Guide RNAs
ABSTRACT Our goal is to develop RNA‐guided engineering of the chloroplast genome using the CRISPR/Cas9 system. We designed chloroplast minigenes to obtain properly sized single guide RNAs (sgRNAs) in tobacco chloroplasts. The sgRNA 5′ end is defined by transcription from an rRNA operon promoter, and its 3′ end by processing a downstream tRNA (trnG) or ...
Malihe Mirzaee +3 more
wiley +1 more source
Evolution‐Inspired Engineering of Diterpene Biosynthesis via Chloroplast Genome Modification
ABSTRACT Terpenes constitute the largest and most structurally diverse class of plant secondary metabolites, with critical roles in plant‐environment interactions and broad industrial applications. Although nuclear genome engineering of terpene pathways has been extensively explored, chloroplast genome engineering remains largely undeveloped, with most
Alessandro Occhialini +6 more
wiley +1 more source
A newly emerged vanB‐VREfm clone (ST117/CT7799) causes an ongoing outbreak in southeastern Austria. The cluster is highly homogenous, even for isolates sampled months apart. Resistance is easily missed via disk diffusion, gradient tests, and microdilution. VITEK 2 testing reliably detects vancomycin‐resistance.
Patrick Forstner +12 more
wiley +1 more source
Biofilm Source Shapes the Tolerance to Short‐Term Ciprofloxacin Exposure
Biofilms sourced downstream of a wastewater treatment plant showed greater tolerance to ciprofloxacin than upstream‐sourced communities. The results suggest that environmental history and community composition influence freshwater biofilm responses to antibiotic stress.
Clara Benavent‐Celma +6 more
wiley +1 more source

