Results 111 to 120 of about 36,524 (294)

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak, Ahmed Javed, Ummi Aiman Rahman, Rumaisa Riaz, Zeeshan Imtiaz, Hassan A. Mirza, Farman U. Khan, Muhid Khattak, Fatima Javid, Abdul Moiz Khan, Adeline L. Roy, Bibek Shrestha   +11 more
wiley   +1 more source

Novel daily disposable therapeutic contact lenses based on chitosan and regenerated silk fibroin for the ophthalmic delivery of diclofenac sodium

Drug Delivery, 2020
The aim of this study was to investigate the possibility of chitosan and regenerated silk fibroin (CS/RSF) blended films as novel biomaterials for daily disposable therapeutic contact lenses based ophthalmic drug delivery system.
Rachasit Jeencham, Manote Sutheerawattananonda, Saowaluk Rungchang, Waree Tiyaboonchai   +3 more
doaj   +1 more source

The Automated Vestibular Rehabilitation System: Normative Data From a Machine Vision‐Guided Platform

The Laryngoscope, EarlyView.
The Automated Vestibular Rehabilitation System (AVRS) is a machine vision‐based tool designed to increase accessibility to vestibular rehabilitation therapy by automating exercise delivery and tracking head‐eye movements in real time. In n = 40 healthy adults, the AVRS accurately measured vestibulo‐ocular reflex (VOR) gain values near physiologic norms
Erin Williams, Felipe Echeverri Tribin, Luis Rodriguez Diaz, Valerie Yunis, Devin Kennedy, Blaine Ayotte, Christopher McKenna, Odile Clavier, Michael Hoffer   +8 more
wiley   +1 more source

Topical Ocular Drug Delivery: The Impact of Permeation Enhancers

Pharmaceutics
Topical ophthalmic drug delivery targeting the posterior segment of the eye has become a key area of interest due to its non-invasive nature, safety, ease of application, patient compliance, and cost-effectiveness.
Gonçalo Santos, Esmeralda Delgado, Beatriz Silva, Berta São Braz, Lídia Gonçalves   +4 more
doaj   +1 more source

In situ gelling systems based on Pluronic F127/Pluronic F68 formulations for ocular drug delivery [PDF]

, 2016
This study evaluated the use of Pluronic F127 and Pluronic F68 as excipients for formulating in situ gelling systems for ocular drug delivery. Thermal transitions have been studied in aqueous solutions of Pluronic F127, Pluronic F68 as well as their ...
Khateb, Kosai Al, Khutoryanskiy, Vitaliy V., Lau, Wing Man, Mussin, Marat N., Ozhmukhametova, Elvira K., Rakhypbekov, Tolebai K., Seilkhanov, Serzhan K.   +6 more
core   +1 more source

Mid‐Infrared Integrated Photonics: Material Platforms and Emerging Applications

Laser &Photonics Reviews, EarlyView.
Mid‐infrared (MIR) integrated photonics enables advanced chemical and biological sensing through the unique absorption features of molecules in the 2–20 µm range. This review highlights recent material advances such as chalcogenide glasses, silicon, and graphene and explores MIR applications in environmental monitoring, medical diagnostics ...
Muhammad Ali Butt, Daniel Pastor Abellán, Ryszard Piramidowicz   +2 more
wiley   +1 more source

Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs

International Journal of Polymer Science, 2011
Soft contact lenses can improve the bioavailability and prolong the residence time of drugs and, therefore, are ideal drug carriers for ophthalmic drug delivery. Hydrogels are the leading materials of soft contact lenses because of their biocompatibility
Xiaohong Hu, Lingyun Hao, Huaiqing Wang, Xiaoli Yang, Guojun Zhang, Guoyu Wang, Xiao Zhang   +6 more
doaj   +1 more source

Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]

, 2017
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz, Alio, Ambrosio, Djalilian, Dogru, Li, Nebbioso, Nebbioso, Patel, Rajan, Solomon, Suzuki, Toda, Wilson, Zhu   +14 more
core   +1 more source

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

Macromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani, José Hurst, Malte Ritter, Philipp Weingarten, Julia Skokowa, Sven Schnichels, Friederike Adams   +6 more
wiley   +1 more source

Ocular Drug Delivery: A Special Focus on the Thermosensitive Approach

Nanomaterials, 2019
The bioavailability of ophthalmic therapeutics is reduced because of the presence of physiological barriers whose primary function is to hinder the entry of exogenous agents, therefore also decreasing the bioavailability of locally administered drugs ...
Simona Sapino, Daniela Chirio, Elena Peira, Elena Abellán Rubio, Valentina Brunella, Sushilkumar A. Jadhav, Giulia Chindamo, Marina Gallarate   +7 more
doaj   +1 more source