Ophthalmic Solutions with a Broad Antiviral Action: Evaluation of Their Potential against Ocular Herpetic Infections [PDF]
Microorganisms, 2022 HSV-1 can be associated with severe and recurrent eye infections characterized by a strong inflammatory response that leads to blepharoconjunctivitis, epithelial and stromal keratitis, and retinal necrosis. The incidence of HSV-1 keratitis is 1.5 million
Carla Zannella +9 more
doaj +2 more sources
Inhibitory Effect of Ophthalmic Solutions against SARS-CoV-2: A Preventive Action to Block the Viral Transmission? [PDF]
Microorganisms, 2021 In 2020, a global pandemic was declared following the spread of SARS-CoV-2, the pathogen responsible for COVID-19. The risk of infection is high due to the ease of transmission, which can occur orally, through droplets, or via contact with contaminated ...
Francesco Petrillo +10 more
doaj +2 more sources
Evaluation of the cytotoxic effects of ophthalmic solutions containing benzalkonium chloride on corneal epithelium using an organotypic 3-D model [PDF]
BMC Ophthalmology, 2009 Background Benzalkonium chloride (BAC) is a common preservative used in ophthalmic solutions. The aim of this study was to compare the cytotoxic effects of BAC-containing ophthalmic solutions with a BAC-free ophthalmic solution using an organotypic 3 ...
Jessen Bart A, Khoh-Reiter Su
doaj +2 more sources
Broad-Spectrum Antimicrobial Activity of Oftasecur and Visuprime Ophthalmic Solutions [PDF]
Microorganisms, 2023 Due to the wide etiology of conjunctivitis, the expensive and time-consuming diagnosis requires new therapeutic strategies with broad-spectrum antimicrobial activity and nonselective mechanisms of action.
Federica Dell’Annunziata +8 more
doaj +2 more sources
Changes of tear film lipid layer thickness by 3% diquafosol ophthalmic solutions in patients with dry eye syndrome [PDF]
International Journal of Ophthalmology, 2019 AIM: To evaluate the quantitatively changes in lipid layer thickness (LLT) when 3% diquafosol eye drop is used for dry eye patients using the tear film interferometer.
Dong-Hyun Kang +7 more
doaj +2 more sources
In Vitro Evaluation of Combined Commercialized Ophthalmic Solutions Against Acanthamoeba Strains [PDF]
Pathogens, 2019 Acanthamoeba is a free-living amoebae genus which is present worldwide in natural and artificial environments. These amoebae are clinically important as causative agents of diseases in humans and other animals such as a fatal encephalitis or a sight ...
María Reyes-Batlle +14 more
doaj +2 more sources
A study on the most prevalent bacterial cause of corneal ulcer and their susceptibility to five common types of ophthalmic antibiotics [PDF]
Trends in Pharmaceutical Sciences, 2020 Purpose: Proper diagnosis of the corneal ulcer is one the most important efforts in the eyes medical urgencies. The aim of this study was to determine the bacteriological profile and in vitro antibiotic resistance of the bacteria isolated from the eyes of
Nazafarin Hatami-Mazinani +3 more
doaj +1 more source
Recalcitrant Pseudomonas Aeruginosa Keratitis with Hyphaema
Case Reports in Ophthalmology, 2021 Purpose: To report a case of recalcitrant pseudomonas keratitis with a rare presentation of hyphaema. Observation: A 45-year-old female was noted to have contact lens-related pseudomonas keratitis with hyphaema.
Amy Chan +3 more
doaj +1 more source
Points to consider when developing drugs for dry eye syndrome [PDF]
Osong Public Health and Research Perspectives, 2023 Changes in both the social environment (e.g., the increased use of electronic media) and the atmospheric environment (e.g., air pollution and dust) have contributed to an increasing incidence of eye disease and an increased need for eye care.
Suyoung Bae, Hosun Seung, Ho Jung Oh
doaj +1 more source
Central Anticholinergic Syndrome Following Excessive Mydriatic Use in an Eight-Year-Old Patient
Trends in Pediatrics, 2021 Cyclopentolate hydrochloride, belonging to a class of drugs known as anticholinergics, is an ophthalmic solution frequently used in ophthalmology clinics because of its cycloplegic and mydriatic effects in both refractions as well as fundus examinations.
Nazan Kaymaz +4 more
doaj +1 more source