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Contact dermatitis to ophthalmic solutions [PDF]
Periorbital and eyelid dermatitis is a recalcitrant and often distressing condition. Allergic contact dermatitis to ophthalmic solutions is an important cause of periorbital and eyelid dermatitis. In this review article, we discuss the allergens involved, the difficulties in patch testing, and the recommended concentrations and vehicles for patch ...
M. Kalavala, A. A. Mughal
openaire +4 more sources
A straightforward size exclusion chromatography (SEC) method was developed and validated for the determination of total polivinylpyrrolidone (PVP) in ophthalmic solutions using the unusual combination of size exclusion chromatography (SEC), ultraviolet ...
Panagiotis Tavlarakis+2 more
openalex +2 more sources
AIM To evaluate the quantitatively changes in lipid layer thickness (LLT) when 3% diquafosol eye drop is used for dry eye patients using the tear film interferometer.
Donghyun Kang+7 more
openalex +2 more sources
Dry eye disease (DED) is a multifactorial disease of ocular surface and tear film, and is a common disorder treated by eye care providers. It is well established that ocular surface inflammation has an important role in the pathophysiology of DED and ...
Rodrigo Carlos de Oliveira+1 more
openalex +3 more sources
In Vivo Pharmacokinetics of Bromfenac Ophthalmic Solution 0.075%, Bromfenac Ophthalmic Solution 0.07%, and Nepafenac/Amfenac Ophthalmic Suspension 0.3% in Rabbits [PDF]
Little is known of the ocular distribution characteristics of currently branded non-steroidal anti-inflammatory drugs (NSAIDs) in the United States. This study was designed to predict the ocular bioavailability characteristics in humans using Dutch Belted rabbits as a surrogate.
Paul C. Cockrum+3 more
openaire +4 more sources
Preservation of Ophthalmic Solutions: A Critical Evaluation [PDF]
S. E. Wright, M. L. Frith
openaire +5 more sources
Broad-Spectrum Antimicrobial Activity of Oftasecur and Visuprime Ophthalmic Solutions
Due to the wide etiology of conjunctivitis, the expensive and time-consuming diagnosis requires new therapeutic strategies with broad-spectrum antimicrobial activity and nonselective mechanisms of action.
Federica Dell’Annunziata+8 more
semanticscholar +1 more source
Clinical Ocular Exposure Extrapolation for Ophthalmic Solutions Using PBPK Modeling and Simulation
Background The development of generic ophthalmic drug products is challenging due to the complexity of the ocular system, and a lack of sensitive testing to evaluate the interplay of physiology with ophthalmic formulations.
Maxime Le Merdy+6 more
semanticscholar +1 more source
In 2020, a global pandemic was declared following the spread of SARS-CoV-2, the pathogen responsible for COVID-19. The risk of infection is high due to the ease of transmission, which can occur orally, through droplets, or via contact with contaminated ...
Francesco Petrillo+10 more
semanticscholar +1 more source
OBJECTIVES: Timolol maleate has been reported to be a safer intraocular pressure (IOP) lowering treatment than latanoprost. The United States Food and Drug Administration approved latanoprostene bunod, a nitric oxide-donating prodrug of latanoprost, for ...
Yulong Wang, Yue Liao, Xin Nie
semanticscholar +1 more source