Results 1 to 10 of about 6,907,227 (184)

Contact dermatitis to ophthalmic solutions [PDF]

open access: yesClinical and Experimental Dermatology, 2012
Periorbital and eyelid dermatitis is a recalcitrant and often distressing condition. Allergic contact dermatitis to ophthalmic solutions is an important cause of periorbital and eyelid dermatitis. In this review article, we discuss the allergens involved, the difficulties in patch testing, and the recommended concentrations and vehicles for patch ...
M. Kalavala, A. A. Mughal
openaire   +4 more sources

Determination of Total Polyvinylpyrrolidone (PVP) in Ophthalmic Solutions by Size Exclusion Chromatography with Ultraviolet-visible Detection

open access: bronzeJournal of Chromatographic Science, 2011
A straightforward size exclusion chromatography (SEC) method was developed and validated for the determination of total polivinylpyrrolidone (PVP) in ophthalmic solutions using the unusual combination of size exclusion chromatography (SEC), ultraviolet ...
Panagiotis Tavlarakis   +2 more
openalex   +2 more sources

Changes of tear film lipid layer thickness by 3% diquafosol ophthalmic solutions in patients with dry eye syndrome

open access: goldInternational Journal of Ophthalmology, 2019
AIM To evaluate the quantitatively changes in lipid layer thickness (LLT) when 3% diquafosol eye drop is used for dry eye patients using the tear film interferometer.
Donghyun Kang   +7 more
openalex   +2 more sources

<p>Practical guidance for the use of cyclosporine ophthalmic solutions in the management of dry eye disease</p>

open access: goldClinical Ophthalmology, 2019
Dry eye disease (DED) is a multifactorial disease of ocular surface and tear film, and is a common disorder treated by eye care providers. It is well established that ocular surface inflammation has an important role in the pathophysiology of DED and ...
Rodrigo Carlos de Oliveira   +1 more
openalex   +3 more sources

In Vivo Pharmacokinetics of Bromfenac Ophthalmic Solution 0.075%, Bromfenac Ophthalmic Solution 0.07%, and Nepafenac/Amfenac Ophthalmic Suspension 0.3% in Rabbits [PDF]

open access: goldOphthalmology and Therapy, 2018
Little is known of the ocular distribution characteristics of currently branded non-steroidal anti-inflammatory drugs (NSAIDs) in the United States. This study was designed to predict the ocular bioavailability characteristics in humans using Dutch Belted rabbits as a surrogate.
Paul C. Cockrum   +3 more
openaire   +4 more sources

Broad-Spectrum Antimicrobial Activity of Oftasecur and Visuprime Ophthalmic Solutions

open access: yesMicroorganisms, 2023
Due to the wide etiology of conjunctivitis, the expensive and time-consuming diagnosis requires new therapeutic strategies with broad-spectrum antimicrobial activity and nonselective mechanisms of action.
Federica Dell’Annunziata   +8 more
semanticscholar   +1 more source

Clinical Ocular Exposure Extrapolation for Ophthalmic Solutions Using PBPK Modeling and Simulation

open access: yesPharmaceutical Research, 2022
Background The development of generic ophthalmic drug products is challenging due to the complexity of the ocular system, and a lack of sensitive testing to evaluate the interplay of physiology with ophthalmic formulations.
Maxime Le Merdy   +6 more
semanticscholar   +1 more source

Inhibitory Effect of Ophthalmic Solutions against SARS-CoV-2: A Preventive Action to Block the Viral Transmission?

open access: yesMicroorganisms, 2021
In 2020, a global pandemic was declared following the spread of SARS-CoV-2, the pathogen responsible for COVID-19. The risk of infection is high due to the ease of transmission, which can occur orally, through droplets, or via contact with contaminated ...
Francesco Petrillo   +10 more
semanticscholar   +1 more source

Comparative evaluation of Latanoprostene Bunod, Timolol Maleate, and latanoprost Ophthalmic Solutions to assess their safety and efficacy in lowering intraocular pressure for the management of Open-Angle Glaucoma

open access: yesClinics, 2020
OBJECTIVES: Timolol maleate has been reported to be a safer intraocular pressure (IOP) lowering treatment than latanoprost. The United States Food and Drug Administration approved latanoprostene bunod, a nitric oxide-donating prodrug of latanoprost, for ...
Yulong Wang, Yue Liao, Xin Nie
semanticscholar   +1 more source

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