Results 41 to 50 of about 20,308 (302)

Age and Sex Variation in the Duration of Action and Corneal Touch Threshold (CTT) following Instillation of 0.5% Topical Ophthalmic Proparacaine and Tetracaine Hydrochlorides

Journal of Ophthalmology, 2021
Purpose. We investigated the effect of age and sex on corneal touch threshold (CTT) and duration of action following administration of 0.5% topical ophthalmic proparacaine and tetracaine hydrochlorides. Methods. A prospective, randomized, subject-masked,
Samuel Kyei, Nana Yaw Abaka Dadzie, Ebenezer Zaabaar, Kwasi Antwi Asamoah Dwomoh, Kofi Asiedu   +4 more
doaj   +1 more source

Vision-Based Eye Image Classification for Ophthalmic Measurement Systems

Sensors, 2022
The accuracy and the overall performances of ophthalmic instrumentation, where specific analysis of eye images is involved, can be negatively influenced by invalid or incorrect frames acquired during everyday measurements of unaware or non-collaborative ...
Giovanni Gibertoni, Guido Borghi, Luigi Rovati   +2 more
doaj   +1 more source

Photonic Nanomaterials for Wearable Health Solutions

Advanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park, Jung Woo Leem, Young L. Kim, Chi Hwan Lee   +3 more
wiley   +1 more source

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

Advanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui, Zining Wang, Zixuan Guo, Hongxia Zhang, Yongxiang Liu, Huanling Zhang, Huan Jin, Feifei Xu, Xiaojuan Wang, Chunyuan Xie, Hui Guo, Tiantian Wang, Yanxun Lin, Qi Zhao, Penghui Zhou, Jing Tan, Jin‐Xin Bei, Peng Huang, Jinyun Liu, Xiaojun Xia   +19 more
wiley   +1 more source

The Antibacterial Effect of a Preservative-free Multi-dose Eye Dropper Using Air Pressure Differentials

Korean Journal of Clinical Laboratory Science
This study aimed to evaluate the antibacterial effects of a newly designed preservative-free multi-dose eye dropper that addresses various shortcomings found in conventional models.
Da-Been LEE, Seung-Lim YOO, Minchul SONG, Mihee NA, Dae-Wui YOON   +4 more
doaj   +1 more source

Dual‐Crosslinked Betaine‐Based Amphiphilic Hydrogel as a Promising Vitreous Substitute: Anti‐Adhesion, Anti‐Fouling, and Anti‐Cell Proliferation

Advanced Science, EarlyView.
A novel multiple cross‐linked betaine‐type amphiphilic polymer hydrogels are developed via in situ free radical copolymerization. The resultant formation, named P(SBMA‐co‐AANa) hydrogel, functions as a vitreous substitute and demonstrates superior performance in optical properties, support capacity, and biocompatibility on a vitrectomized rabbit model.
Yuting Cai, Yun Tan, Jian Cao, Xiaoyuan Zhou, Xingyuan Li, Jianghua Li, Chuntai Liu, Yi Zhang, Yun Li   +8 more
wiley   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Effectiveness of autologous serum eye drops in the treatment of corneoconjunctival burns

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Background: ocular burns are a health problem since they have a relevant place in the ophthalmological practice.Objective: to assess the effectiveness of 50 % autologous serum eye drops combined with the conventional treatment of corneoconjunctival burns
Yanier Serrano-García, Alena de los Ángeles Vejerano-Duany, María Del Carmen González-Fernández, Leonor Gallardo-Roca, Taimi Miranda-Vergara   +4 more
doaj  

The chemotactic properties of various topical brimonidine tartrate ophthalmic preparations

BMC Pharmacology and Toxicology, 2020
Background The study aimed to evaluate and compare the leukocyte chemotactic activities of various brimonidine tartrate (BT) eye drop formulations. Methods A 96-well dot-blot platet using a Boyden-style well was used to study the chemotactic effects of ...
Ruiz Simonato Alonso, Helena Parente Solari, Eduardo de França Damasceno, Miguel Noel Nascentes Burnier, Marcelo Palis Ventura   +4 more
doaj   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source