Results 81 to 90 of about 7,961,527 (324)

Microbial contamination and biofilm formation in ophthalmic solutions and ophthalmic instruments at optometry practice [PDF]

Background: Maintaining sterility and preventing microbial contamination are critical in optometry, where multiple surfaces, devices, and solutions contact the patient's eyes, posing an infection risk.
Abdul Rahim, Muhammad Afzam Shah, Abd Karim, Aina Balqis, Ahmad Yusof @ Hanafi, Hanani, Yusof @ Alias, Firdaus, Buari, Noor Halilah, Saad Al Saadoun, Aisyah   +5 more
core  

Design against nature

, 2003
The process of disinfecting pits technology against nature. This issue is considered through examination of the design and development of a microwave disinfecting system for contact lenses.
Crabbe, A
core   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

Physicochemical Stability of a Novel Tacrolimus Ophthalmic Formulation for the Treatment of Ophthalmic Inflammatory Diseases

, 2022
Tacrolimus is an immunosuppressant used to treat a large variety of inflammatory or immunity-mediated ophthalmic diseases. However, there are currently no commercial industrial forms available that can provide relief to patients.
Marion Barrieu, Le Basle, Yoann, Mireille Jouannet, Bouattour, Yassine, Philip Chennell, Chennell, Philip, Yassine Bouattour, Mathieu Wasiak, Yoann Le Basle, Jouannet, Mireille, Barrieu, Marion, Sautou, Valérie, Mouloud Yessaad, Yessaad, Mouloud, Wasiak, Mathieu, Valérie Sautou   +15 more
core   +1 more source

Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip

Advanced Science, EarlyView.
In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao, Dongyu Xu, Minhui Lu, Yuanjin Zhao   +3 more
wiley   +1 more source

Ophthalmic salines and the acidity question

, 1990
What acidity (minimum pH) will most patients tolerate when using ophthalmic salines? After sone decades of trying to answer that question (and many continue to try), it is becoming increasingly evident that the question rather then the answer may be ...
Carney, Leo G., Hill, Richard M., Habenicht, Brenda L.   +2 more
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Toxicity of Ophthalmic Solutions, Benzalkonium Chloride and UV Radiation on Human Corneal Epithelial Cells in vitro [PDF]

, 2015
The purpose of this work was to develop a sensitive in vitro method for ocular toxicity testing; and to use this method to assess the individual and combined effects of ophthalmic solutions, benzalkonium chloride (BAK), and ultraviolet (UV) radiation on ...
Xu, Manlong
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The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Efficacy of ophthalmic solutions to detach adhering Pseudomonas aeruginosa from contact lenses

, 1998
Purpose. To compare the efficacies of two all-in-one contact lens (CL) cleaning solutions and a detergent mixture on the detachment of a pathogenic bacterium adhering to two types of contact lenses in the absence and presence of a tear film.
van der Mei, HC, Busscher, HJ, van Rij, G, Landa, AS, van der Mei, HC; id_orcid   +4 more
core   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Advanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan   +6 more
wiley   +1 more source