Results 111 to 120 of about 698,290 (348)

Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]

, 2011
Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H., Koss, Michael Janusz, Pfister, Marcel   +2 more
core  

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Correlation Between Macular Microstructural Changes with Disease Staging and Visual Acuity in Diabetic Retinopathy

International Journal of General Medicine
Wenhua Zhang, Feng Zhang, Yezhen Yang, Jiamin Cao, Ziyi Zhu Department of Ophthalmology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, People’s Republic of ChinaCorrespondence: Ziyi Zhu, Department of Ophthalmology, The ...
Zhang W, Zhang F, Yang Y, Cao J, Zhu Z
doaj  

The Ophthalmological Manifestations of Various Inborn Errors of Metabolism: A Narrative Review

Journal of Pediatrics Review, 2021
Context: Inborn errors of metabolism or Inherited Metabolic Disorders (IMD) are a class of genetic disorders that occur because of single-gene defects. Evidence Acquisition: In this narrative review article, the authors searched Institute for Scientific ...
Abdolreza Medghalchi, Afagh Hassanzadeh Rad, Setila Dalili   +2 more
doaj  

Artificial intelligence in ophthalmology: The path to the real-world clinic

Cell Reports Medicine, 2023
Zhongwen Li, Lei Wang, Xuefang Wu, Jiewei Jiang, Wei Qiang, He Xie, Hongjian Zhou, Shanjun Wu, Yi Shao, Wei Chen   +9 more
semanticscholar   +1 more source

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

Extensive Visually-Significant Stellate-Like Pseudoexfoliative Deposition on an Intraocular Lens Implant of Pseudophakic Eye: Insights for Unusual Presentation [Response to Letter]

Clinical Optometry
Abdelwahab Aleshawi,1 Mohammad Ali Al Qudah,1 Hamad Alazmi,2 Ahmed Al Sharie,2 Haya Sufyan Elnagar Jnr,3 Hosni Alzoubi,1 Saad Almutairi,2 Seren Al Beiruti,1 Rami Al-Dwairi1 1Department of Special Surgery, Division of Ophthalmology, Faculty of Medicine ...
Aleshawi A, Al Qudah MA, Alazmi H, Al Sharie A, Elnagar Jnr HS, Alzoubi H, Almutairi S, Al Beiruti S, Al-Dwairi R   +8 more
doaj  

A Novel Zinc(II) Complex for Sonodynamic Therapy Induces Pyroptosis of Breast Cancer Cells and Enhances Anti‐Tumor Immune Response

Advanced Science, EarlyView.
Although Zinc(II) complexes are effective in photodynamic therapy, their efficacy is limited by the poor tissue penetration of light. This work introduces a novel zinc(II) complex for sonodynamic therapy. Under ultrasound activation, it generates substantial singlet oxygen, induces pyroptosis in breast cancer cells, and promotes anti‐tumor immune ...
Sijie Wen, Dongsheng Tang, Lingpu Zhang, Hanchen Zhang, Zheng Cao, Kong Wai Tan, Xiaojun Wang, Haihua Xiao, Kun Shang   +8 more
wiley   +1 more source

Associations of Sleep Duration and Social Jetlag with Dry Eye Disease in Chinese School-Aged Children and Adolescents

Nature and Science of Sleep
Yuzhu Luo,1,* Yuting Gao,1,* Zhong Guan,1,* Heting Liu,1 Shuman Tao1– 5 1Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, People’s Republic of China; 2MOE Key Laboratory of ...
Luo Y, Gao Y, Guan Z, Liu H, Tao S
doaj  

Robotic surgery in eye care: A comprehensive review

Journal of Clinical Ophthalmology and Research
Robotic surgery represents an innovative frontier in ophthalmology, aiming to enhance precision, reduce surgical complications, and expand the potential for minimally invasive procedures.
Jatinder Bali, Nandan Bali
doaj   +1 more source