Results 111 to 120 of about 682,776 (395)

Single‐Cell Transcriptome Analysis Reveals That Hmga2 Regulates Neuroinflammation and Retinal Function by Modulating Müller Cell Autophagy Through PI3K/AKT Signaling Following MCAO‐Induced Retinal Ischemia

Advanced Science, EarlyView.
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv, Juzheng Yuan, Zhe Ruan, Ya‐nan Dou, Hongchen Zhang, Xiaowei Fei, Leiying Chen, Zehan Zhang, Kai Yang, Xiuquan Wu, Zhou Fei, Fei Fei   +11 more
wiley   +1 more source

Drug-Induced Sleep Endoscopy and Its Recent Clinical Applications in Combination with Other Procedures in Children: A Narrative Review

Nature and Science of Sleep
Zhixian Xiao,1,* Xing Li,2,* Li Zhou,3,* Xiaocui Long,4 Li Tian,3 Weiqi Li2 1Department of Otorhinolaryngology-Head and Neck Surgery, Affiliated Meishan Hospital of Chengdu University of TCM, Meishan, People’s Republic of China ...
Xiao Z, Li X, Zhou L, Long X, Tian L, Li W   +5 more
doaj  

The Ophthalmological Manifestations of Various Inborn Errors of Metabolism: A Narrative Review

Journal of Pediatrics Review, 2021
Context: Inborn errors of metabolism or Inherited Metabolic Disorders (IMD) are a class of genetic disorders that occur because of single-gene defects. Evidence Acquisition: In this narrative review article, the authors searched Institute for Scientific ...
Abdolreza Medghalchi, Afagh Hassanzadeh Rad, Setila Dalili   +2 more
doaj  

Informed consent in refractive surgery: in-person vs telemedicine approach. [PDF]

, 2018
Purpose:The aim of this study was to compare the quality of consent process in refractive surgery between patients who had a preoperative consent discussion with the surgeon using a telemedicine approach and those who had a face-to-face discussion ...
Hannan, Stephen J, Pelouskova, Martina, Schallhorn, Julie M, Schallhorn, Steven C, Teenan, David   +4 more
core   +1 more source

Drug Delivery Technologies for the Treatment of Age‐Related Macular Degeneration

Advanced Science, EarlyView.
There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
J Jesus Rodriguez‐Cruz, Jessica Cutrufello, Michael Lam, Shreya Nallaparaju, Nicholas A. Peppas   +4 more
wiley   +1 more source

Recent Achievements and Perspectives in Smart Nano-in-Micro Platforms for Ocular Disease Treatment

International Journal of Nanomedicine
Yuhan Huang,1,* Dan Yan,1,* Weijie Ouyang,1,2,* Jiaoyue Hu,1,3 Zuguo Liu1,3,4 1Xiamen University Affiliated Xiamen Eye Center; Fujian Provincial Key Laboratory of Ophthalmology and Visual Science; Fujian Engineering and Research ...
Huang Y, Yan D, Ouyang W, Hu J, Liu Z
doaj  

Refractive Index‐Corrected Light‐Sheet Microscopy for Macro‐View Cardiovascular Imaging

Advanced Science, EarlyView.
A refractive index‐corrected light‐sheet fluorescence microscopy system enables macro‐view cardiovascular imaging across organs, adapting to refractive index variations from different optical clearing protocols. By integrating axial sweeping, multi‐view imaging, and a sealed chamber, it extends the field of view, enhances isotropy, and improves safety.
Enbo Zhu, Yaran Zhang, Peng Zhao, Jae Min Cho, Zhaoqiang Wang, Yan‐Ruide Li, Jing Wang, Samuel Margolis, Shaolei Wang, Lili Yang, Alison Chu, Yuhua Zhang, Liang Gao, Tzung K. Hsiai   +13 more
wiley   +1 more source

Refractive Predictability After Keratorefractive Lenticule Extraction Using a New Nomogram Creation Software Tool Compared to a Matched Control

Clinical Ophthalmology
Qi Wan, Ran Wei, Jing Tang, Ying-ping Deng, Ke Ma Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu, People’s Republic of ChinaCorrespondence: Ying-ping Deng, Department of Ophthalmology, West China Hospital of Sichuan ...
Wan Q, Wei R, Tang J, Deng YP, Ma K
doaj  

Latanoprost with high precision, piezo-print microdose delivery for IOP lowering: clinical results of the PG21 study of 0.4 µg daily microdose. [PDF]

, 2018
Background:Topical high-precision piezo-print delivery of microdoses of latanoprost achieved significant IOP reduction consistent with the eyedropper effect but with a 75% reduced exposure to drugs and preservatives.
Ianchulev, Tsontcho, Kramm, Robert L, Lin, Shan, Pasquale, Louis R, Tsai, James C, Weinreb, Robert N   +5 more
core  

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

Advanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang, Yining Sun, Xintong Yu, Ruoqi Wang, Yuting Zhang, Jinjie Yu, Shuang Xie, Yujia Cai, Yuhong Luo, Wei Chen   +9 more
wiley   +1 more source