Results 141 to 150 of about 539,380 (315)

Enhancing ophthalmology students’ awareness of retinitis pigmentosa: assessing the efficacy of ChatGPT in AI-assisted teaching of rare diseases—a quasi-experimental study

Frontiers in Medicine
BackgroundRetinitis pigmentosa (RP) is a rare retinal dystrophy often underrepresented in ophthalmology education. Despite advancements in diagnostics and treatments like gene therapy, RP knowledge gaps persist.
Jiamu Zeng, Jiamu Zeng, Kexin Sun, Peng Qin, Shulin Liu   +4 more
doaj   +1 more source

Effectiveness of Novel Approaches to Ophthalmology Education in Medical Schools: A Systematic Review and Meta-Analysis

Purpose Effective teaching is often described as being the single most important indicator of student achievement. Due to global reductions in time allocated towards ophthalmology teaching in medical school there is a pressing need for more effective ...
Agar, Ashish, Spencer, Sascha, Choy, William, Dr, Kalas, Dylan S, Huang, Pin-Hsiang, Shulruf, Boaz   +5 more
core   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Study of Macular Microvascular Changes in Patients with Symptomatic Lacunar Cerebral Infarction Using Viaoptical Coherence Tomography Angiography (OCTA)

International Journal of General Medicine
Meishuang Li,1– 4,* Huiyu Xi,1,3,4,* Rongrong Guan,5,* Yalu Liu,1,3,4 Lina Guan,1,3,4 Dandan Zong,1,4,6 Nuan Wang,1,4 Haiyang Liu1,3,4 1Department of Ophthalmology, Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University,
Li M, Xi H, Guan R, Liu Y, Guan L, Zong D, Wang N, Liu H   +7 more
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Core Entrustable Professional Activities and Qualities for Entering Ophthalmology Residency: A National Survey

Background Little information is available regarding the competencies and qualities expected of incoming ophthalmology residents by ophthalmology residency program leadership.
Law, Janice C., Chennupati, Shravika L., Lindsey, Jennifer L.   +2 more
core   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

Effectiveness of Trabeculectomy in Primary Open-Angle Glaucoma with Low Preoperative Intraocular Pressure

Clinical Ophthalmology
Hiroshi Katayama, Naoki Tojo, Naoki Toyoda, Atsushi Hayashi Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, JapanCorrespondence: Atsushi Hayashi, Department of Ophthalmology, Graduate ...
Katayama H, Tojo N, Toyoda N, Hayashi A
doaj  

Ophthalmology Career Choices Among Medical Students in Africa: A Cross-Sectional Survey of 36 Countries

Purpose To explore the factors influencing medical students\u27 choice of ophthalmology as a specialty in Africa. Design This was a cross-sectional, mixed methods survey study involving medical students in 36 African countries.
Flaharty, Kathryn, Tabin, Geoff, Tiertoore, Nina, Wubishet, Hellen, Abdu, Amani, Bernard, Alec, Mengesha, Dawit, Mullen, Evan, Abdullahi, Hamdi, Golnik, Karl, Tolera, Abdi, Gebeyehu, Tadael, Adem, Yesuf   +12 more
core   +1 more source

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

Advanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu, Jingfan Wang, Pengfei Ge, Qinyuan Gu, Hongying Li, Yuanyuan Fan, Haiyue Xie, Yangyang Lu, Yifan Lin, Xinjing Wu, Chengkun Wang, Ping Xie, Zizhong Hu   +12 more
wiley   +1 more source

Longitudinal Biometric Changes and Intraocular Lens Calculation Formula Accuracy in Delayed Cataract Surgery Cases

Clinical Ophthalmology
Shohei Nishida,1 Akira Hirata,2 Yasuya Inomata1 1Department of Ophthalmology, Inomata Eye Clinic, Kumamoto City, Kumamoto, Japan; 2Department of Ophthalmology, Hayashi Eye Hospital, Fukuoka City, Fukuoka, JapanCorrespondence: Yasuya Inomata, Inomata Eye ...
Nishida S, Hirata A, Inomata Y
doaj