Results 61 to 70 of about 1,415 (153)

Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Yao Wang, Junxian Zhao, Fangxia Zou, Wanglin Jiang, Jianzhao Zhang, Pengfei Yu, Liang Ye, Xiaolin Sun, Chunmei Li, Jingwei Tian   +9 more
wiley   +1 more source

Nailfold capillary phenotypes distinguish juvenile myositis subtypes and associate with disease activity

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Nailfold capillaroscopy is a non‐invasive imaging tool that can aid in the diagnosis and monitoring of juvenile myositis. Branched nailfold capillary morphology is more common in juvenile myositis patients, particularly those positive for TIF1γ+ autoantibodies. Juvenile myositis patients with more active disease demonstrate increased microhaemorrhages,
Nicholas McClellan, Li Chen, Sophia Matossian, Aurora Rynda, Kirsten Grant, Erin Janssen, J. Michelle Kahlenberg, Jessica L. Turnier   +7 more
wiley   +1 more source

Ensino de oftalmologia na graduação médica: Estudo comparativo de aprendizado na oftalmoscopia direta com oftalmoscópio convencional e de campo amplo (Panoptic) Teaching ophthalmology at university medical undergraduate course: Comparative study of direct ophthalmoscopy between conventional ophthalmoscope and wide field ophthalmoscope (panoptic) as evaluation method

Revista Brasileira de Oftalmologia, 2009
Objetivo: Comparação da facilidade de aprendizado na realização da oftalmoscopia direta pelos alunos da graduação médica com o uso do oftalmoscópio convencional e do Panoptic. Métodos: Realizou- se um estudo comparativo da facilidade de aprendizado entre
Eduardo de França Damasceno, Nadyr Antonia Pereira Damasceno, Adroaldo de Alencar Costa Filho   +2 more
doaj   +1 more source

Vision and Foraging in Structurally Complex Habitats: Common Moorhens (Gallinula chloropus) See the Way Ahead

Ecology and Evolution, Volume 16, Issue 9, September 2026.
This study examines how common moorhens balance foraging and predator detection through their visual field configuration. It finds they have a narrow but vertically elongated binocular field for precise feeding, alongside near‐panoramic monocular vision for wide environmental awareness.
Steven J. Portugal, Eleanor A. Lucas, Simon Potier, Gérard Rocamora, Graham R. Martin   +4 more
wiley   +1 more source

Compound Heterozygous PCDH15 Variants Associated With Cone‐Rod Dystrophy in a Chinese Pedigree

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
This study represents the first report suggesting a genotype–phenotype relationship between PCDH15 genetic variants and isolated retinal manifestations absent auditory impairment or syndromic features, thereby providing preliminary evidence that may broaden the mutational spectrum associated with this gene.
Lei Zhang, Qianfeng Wang, Haiyan Wang, Wei Jia, Bowen Zhang, Ru Wang, Wei Qiang, Shuwei Bai   +7 more
wiley   +1 more source

Bilateral Blepharoplasty and Shortening of the Third Eyelid Cartilage as Treatment for Chronic Corneal Ulceration in a Giant Rabbit—A Case Report

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT This case report describes the clinical presentation and successful surgical management of a combined dorsal entropion‐ectropion macroblepharon with an elongated and folded nictitating membrane in a 2‐year‐old male giant rabbit. The rabbit initially presented with bilateral chronic, recurrent corneal erosions secondary to abnormal eyelid and ...
Anja Suter, Angelie Shukla, Lara Scherer, Sandro Stalder, Antonella Rampazzo   +4 more
wiley   +1 more source

Transconjunctival Orbitotomy as Surgical Management of an Orbital Lipoma in a Dog

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Orbital lipomas are rare in dogs and may pose diagnostic and surgical challenges. This report describes the case of a 14‐year‐old female Border Collie presenting chronic exophthalmos caused by a retrobulbar mass. On ophthalmic examination, the animal maintained bilateral vision despite chronic exposure of the right ocular surface.
Lucas de Souza Viana, Francis Arthur Seco Prando, Isabela Pessôa Barbieri Bastos, Adriano de Sales Araujo, Bruno Alberigi   +4 more
wiley   +1 more source

Conjunctival Sac‐Derived Lactobacillus mucosae MM‐1 Metabolite Indole‐3‐Lactic Acid Attenuates Lens‐Induced Myopia in Mice via AHR Activation and TGF‐β/Smad Inhibition

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
This study proposes a ‘conjunctival sac microecology‐metabolite‐scleral remodelling’ regulatory axis, highlighting the potential role of conjunctival sac microbiota in maintaining ocular surface health and regulating lens‐induced myopia in mice, providing an important theoretical foundation for the development of microbiome‐based interventions for ...
Yanqing Li, Qiuyu Wu, Xilong Zhang, Luchuan Liu, Leiping Ding, Jingjing Xu, Chiwen Cheng, Yangyang Peng, Kang Yu, Wen Yao, Yijie Pi, Jiale Li, Di Wu, Jing Wei, Yifeng Yu, Tingtao Chen   +15 more
wiley   +1 more source

Outcomes and complications of sponges versus tires for scleral buckling in primary rhegmatogenous retinal detachment: The Manchester Buckle Study

Acta Ophthalmologica, Volume 104, Issue 5, Page e538-e543, August 2026.
Abstract Purpose To compare preoperative characteristics and postoperative anatomical and functional outcomes of scleral buckle surgery using sponges versus tires, as well as explant‐related complications and the frequency of explant removal. Methods This retrospective study included patients with primary rhegmatogenous retinal detachment (RRD) who ...
Peter Kiraly, Myrta Lippera, Naseer Ally, Ritu Agarwal, George Moussa, Tsveta Ivanova, Felipe Dhawahir‐Scala, Niall Patton, George Turner, Stephen Charles, Assad Jalil, Kirti M. Jasani   +11 more
wiley   +1 more source

Wide-field fundus autofluorescence corresponds to visual fields in chorioretinitis patients

Clinical Ophthalmology, 2011
Florian Seidensticker1, Aljoscha S Neubauer1, Tamer Wasfy1,2, Carmen Stumpf1, Stephan R Thurau1,*, Anselm Kampik1, Marcus Kernt1,*1Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany; 2Department of Ophthalmology, Tanta University,
Seidensticker F, Neubauer AS, Wasfy T, Stumpf C, Thurau SR, Kampik A, Kernt M   +6 more
doaj