Results 141 to 150 of about 269,209 (316)
N‐Pyrrolidino fluetonitazene, a synthetic opioid, was identified and characterized in a nasal spray using GC‐MS, LC‐QTOF‐MS, NMR and FT‐IR. ABSTRACT Detection of drugs in non‐biological samples serves as a fundamental basis for identifying emerging trends in the field of new psychoactive substances and provides valuable information for optimizing ...
Fabian Picht +4 more
wiley +1 more source
The Opioid Crisis—Not Just Opioids Anymore
Jeffrey, Brent, Stephanie T, Weiss
openaire +2 more sources
The current study compared personality characteristics and cognitive functioning (specifically, attentional bias) in a sample of adults who had experienced childhood trauma (the Trauma group) and a matched healthy control group.
Christ, Bjorn U
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Barriers and Needs of Opioid Prevention, Treatment, and Recovery Providers
This is a research brief describing findings of a needs assessment with individuals who provided prevention, treatment, or recovery services for opioid use in rural Washington ...
Northwest Rural Opioid Technical Assistance Collaborative
core +1 more source
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão +4 more
wiley +1 more source
Naloxone antagonizes the local antihyperalgesic effect of fentanyl in burnt skin of healthy humans
The aim of this study was to investigate local opioid effects in the inflamed skin of healthy human volunteers. To induce inflammation, the circular tip of a 10-mm-diameter probe was heated to 48°C and applied for 120 seconds to a site on each forearm of
Hammond, G.R. +2 more
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Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose
A single oral dose of diphenhydramine and cyclizine can be quantified in human head hair for a minimum of 5 months and, in certain cases, for up to 1 year following intake. Among 12 study participants, the measured concentrations ranged from 0 to 610 pg/mg within 1 year post‐intake.
Jan Bílek +3 more
wiley +1 more source
Assessing benefits and harms of opioid therapy [PDF]
Patients with pain should receive treatment that provides the greatest benefit. Opioids are not the first-line therapy for chronic pain outside of active cancer treatment, palliative care, and end-of-life care. Evidence suggests that nonopioid treatments,
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In a randomized, double‐blind, placebo‐controlled study of oral dried kratom leaf powder in healthy kratom‐naive adults, no participants met the clinically meaningful opioid withdrawal threshold; abuse‐related treatment‐emergent adverse events occurred more frequently at higher doses but were generally mild and resolved without sequelae; and no serious
Marion Coe +5 more
wiley +1 more source
The opioid placebo analgesia is mediated exclusively through mu-opioid receptor in rat
Placebo analgesia is one of the most robust and best-studied placebo effects. Recent researches suggest that placebo analgesia activated the m-opioid receptor signalling in the human brain.
Zhang, Wen-Cai +3 more
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