Results 141 to 150 of about 313,201 (307)
Unemployment and opioid overdose death patterns in the United States from 2017 to 2019
Interdisciplinary Journal of Epidemiology and Public HealthIntroduction: Unemployment has been linked to increased opioid-related harms such as opioid overdose deaths. Identifying hotspots and coldspots across the United States (US) can be crucial to understanding health resources and leveraging strategies ...
Rana Khafagy +2 more
doaj +1 more source
, 2018 "July 2018." Includes bibliographical reference."While Kansas is not experiencing the dramatic increase in opioid-related morbidity and mortality as compared to other states, it is a growing and emerging threat that requires state level preparedness ...
Kansas Prescription Drug and Opioid Advisory Committee.
core +1 more source
Ancestral Vertebrate Complexity of the Opioid System
, 2015 The evolution of the opioid peptides and nociceptin/orphanin as well as their receptors has been difficult to resolve due to variable evolutionary rates.
Dan Larhammar +5 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai +12 more
wiley +1 more source
Prevalence of prescription opioid analgesic use among adults : United States, 2013\u20132016 [PDF]
Prescription opioid analgesics are used to treat pain resulting from a variety of health conditions, surgery, and injury. However, opioid-related deaths have emerged as a public health issue (1), and efforts to monitor prescription opioid analgesic use ...
core
Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta
Clinical Pharmacology &Therapeutics, EarlyView.Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung +12 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Young‐Mi Ah +4 more
wiley +1 more source
CYP2D6‐Guided Opioid Therapy for Chronic Pain: A Multi‐Center Pragmatic Randomized Controlled Trial
Clinical Pharmacology &Therapeutics, EarlyView.The analgesic effectiveness of several opioids depends on CYP2D6‐mediated metabolism to more active opioid receptor agonists. CYP2D6 activity is impacted by genetic variability and medications that inhibit CYP2D6. We conducted a pragmatic, multi‐center, randomized, controlled trial to determine whether CYP2D6‐guided opioid prescribing improves chronic ...
Todd C. Skaar +255 more
wiley +1 more source
Magnesium\'s efficacy alone and in combinations in reducing perioperative pain and opioid consumption: A comprehensive narrative review [PDF]
Journal of Clinical and Basic ResearchBackground: Postoperative pain poses a high risk of psychological and physical trauma to surgical patients. Magnesium sulfate (MgSO₄) is inexpensive, safe, and has been used in many anesthesia procedures to evaluate its role in reducing perioperative ...
Tahseen Assad Hasan +6 more
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