Results 211 to 220 of about 593,453 (414)

Amniotic Fluid Ingestion Enhances\ud Opioid-Mediated But Not\ud Nonopioid-Mediated Analgesia [PDF]

open access: yes, 1990
Ingestion of amniotic fluid or placenta by rats has been shown to enhance several types of opioid-mediated analgesia: that induced by morphine, footshock, vaginal/cervical stimulation, and late pregnancy.
Barton, Debra   +2 more
core  

In-vivo studies on kappa opioid receptors [PDF]

open access: green, 1986
Alan Cowan, Debra E. Gmerek
openalex   +1 more source

Editorial: Opioids and opioid-use disorders

open access: yesFrontiers in Pharmacology, 2023
Giordano de Guglielmo   +5 more
openaire   +4 more sources

Dose Determinations at Drug Approval Reviews: FDA‐Approved Drugs in Past 5 Years

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Drug dose appropriateness is one of the most discussed issues in regulatory reviews. We analyzed dose determinations during Food and Drug Administration (FDA) drug reviews to determine whether there were changes between the proposed and approved doses of new molecular entities (NMEs), including cases where postmarketing dose‐finding studies were ...
Sachiko Mita, Shunsuke Ono
wiley   +1 more source

Anatomical relationship between opioid peptides and receptors in rhesus monkey brain [PDF]

open access: green, 1984
Michael E. Lewis   +3 more
openalex   +1 more source

Drug‐Event Pairs as Indicators for the Detection of Adverse Drug Reactions during Hospitalization in Routinely Collected Electronic Data Sources

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund   +5 more
wiley   +1 more source

Adverse Effects of Opioid Dependency on Central and Peripheral Aspects of the Neuromuscular System

open access: yes, 2019
Prevalence of chronic pain and health care costs have caused an escalation of opioid dependency. The current national crisis involving opioid dependency and drug overdose are growing problems that need to be addressed.
Yang, Cindy
core  

Opioid peptides derived from food proteins. The exorphins

open access: hybrid, 1979
C. Zioudrou   +2 more
openalex   +1 more source

Letter on Rockett's et al., manuscript: Fatal self-injury in the United States, 1999–2018: Unmasking a national mental health crisis

open access: yesEClinicalMedicine, 2021
Julian Santaella-Tenorio   +4 more
doaj  

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