Abstract Background Pancreatic enzyme insufficiency (PEI) contributes to symptom burden and malnutrition in advanced pancreatic cancer (aPC). We aimed to evaluate the impact of pancreatic enzyme replacement therapy (PERT) on symptom burden and weight during chemotherapy.
Pamela N. Klassen +6 more
wiley +1 more source
Reframing Buprenorphine as a Pharmacologic Modifier of Opioid-Induced Respiratory Depression in the Fentanyl Era. [PDF]
Bahji A +4 more
europepmc +1 more source
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu +13 more
wiley +1 more source
Samidorphan sadness: does the addition of samidorphan to olanzapine have prodepressive effects? [PDF]
Parkerson JA +3 more
europepmc +1 more source
ABSTRACT Objective This study aimed to evaluate the association of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) with risks of osteoporosis, major osteoporotic fractures, and degenerative musculoskeletal disorders in nondiabetic adults with obesity compared with other obesity medications.
Jie‐Syuan Wu +5 more
wiley +1 more source
Superficial parasternal intercostal plane block with ropivacaine versus placebo for opioid exposure after cardiac surgery (EPOCH CardioLink-10): a multicentre, double-blind, randomised trial. [PDF]
Alli A +31 more
europepmc +1 more source
Perioperative Opioid Use and Risk of Persistent Use After Common Otolaryngologic Procedures
Abstract Objective The objective of this study was to evaluate the incidence of perioperative opioid prescription and the development of new persistent opioid usage in patients prescribed perioperative opioids for common otolaryngological procedures. Study Design Retrospective cohort study. Setting TriNetX US Collaborative Research Network. Methods The
Michael Liu +3 more
wiley +1 more source
Effect of Buddhist music on intraoperative and postoperative opioid requirements during general anesthesia: A randomized controlled pilot study. [PDF]
Hsu WT +4 more
europepmc +1 more source
Mental Health Risk Factors for Postoperative Pain in Head and Neck Free Flap Reconstruction Patients
Abstract Objective Head and neck cancer (HNC) surgery is associated with postoperative pain and comorbid mental health disorders (MHDs). This study assessed predictors of postoperative pain and inpatient pain service consultation following free flap reconstruction (FFR). Study Design Retrospective cohort. Setting Single‐institution database.
Daniel R. S. Habib +8 more
wiley +1 more source

