Results 11 to 20 of about 52,122 (312)
Alcohol use in opioid agonist treatment [PDF]
Addiction Science & Clinical Practice, 2016 Alcohol misuse among individuals receiving agonist treatment for an opioid use disorder is common and is associated with significant morbidity and mortality. At present, though substantial research highlights effective strategies for the screening, diagnosis and management of an alcohol or opioid use disorder individually, less is known about how best ...
Nolan, Seonaid, Klimas, Jan, Wood, Evan
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Opioid Agonist Treatment for Patients With Dependence on Prescription Opioids
JAMA, 2017 Are different opioid agonist treatments (eg, methadone vs buprenorphine) associated with differences in efficacy for treating prescription opioid dependence, and is long-term maintenance of opioid agonist treatment associated with differences in efficacy compared with opioid taper or psychological treatments alone?For patients who are dependent on ...
Nielsen, S, Larance, B, Lintzeris, N
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Advances in the delivery of buprenorphine for opioid dependence
Drug Design, Development and Therapy, 2017 Richard N Rosenthal,1 Viral V Goradia2 1Department of Psychiatry, Addiction Institute at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, 2Department of Psychiatry, Upstate Medical University, Syracuse, NY, USA Abstract: Opioid use ...
Rosenthal RN, Goradia VV
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k-Opioid diuretic effects of tifluadom, a benzodiazepine opioid agonist
Journal of Pharmacy and Pharmacology, 1984 Abstract Tifluadom produced a dose-related (0·08–5 mg kg−1) diuresis in normally hydrated rats. This diuretic effect was antagonized by k-antagonist doses of naloxone and blocked by morphine administration. This is further in-vivo evidence that tifluadom is a fairly specific k-opioid agonist.
J David Leander
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Research and development of κ opioid receptor agonists and δ opioid receptor agonists
Pharmacology & Therapeutics, 2020 Delta opioid delta receptor (DOP) agonists were expected to be analgesics and many researchers tried to develop the SNC80 derivatives. However, the derivatives were dropped at the stage of early clinical trials because of undesirable side effects and weak analgesia.
Hiroshi, Nagase, Akiyoshi, Saitoh
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Use and misuse of opioid agonists in opioid addiction
Cleveland Clinic Journal of Medicine, 2017 Although methadone (an opioid agonist) and buprenorphine (a partial opioid agonist) have evidence to support their use in treating opioid use disorder, they remain misunderstood and underutilized. In this article, we outline the risks and benefits of using these drugs as maintenance therapy in opioid-dependent patients.
Vania, Modesto-Lowe +3 more
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The role of opioid peptides in the regulation of secretin-stimulated bile secretion
Бюллетень сибирской медицины, 2006 Influence of intraperitoneal dalargin (dand m-opioid agonist), DADLE (d-opioid agonist), DAGO (m-opioid agonist) and U50488 (k-opioid agonist) on bile secretion which is stimulated by secretin was studied in sharp experiments on white rats.
M. A. Medvedev, I. V. Roudin
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Novel Opioids in the Setting of Acute Postoperative Pain: A Narrative Review
Pharmaceuticals, 2023 Although traditional opioids such as morphine and oxycodone are commonly used in the management of acute postoperative pain, novel opioids may play a role as alternatives that provide potent pain relief while minimizing adverse effects.
Ashley Wang +5 more
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Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonist [PDF]
, 2013 Since the discovery of the endomorphins (EM), the postulated endogenous peptide agonists of the mu-opioid receptors, several analogues have been synthesized to improve their binding and pharmacological profiles.
Murányi Marianna +25 more
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Substance Abuse Treatment, Prevention, and Policy, 2019 Objective The objective was to characterize the relationship between geography, concurrent psychiatric services, all-cause mortality, and acute health care use for individuals enrolled in Opioid Agonist Treatment, in Ontario, Canada. Methods We conducted
Kristen A. Morin +7 more
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