Results 121 to 130 of about 22,201 (271)

Facilitators of initiating opioid agonist treatments reported by physicians working in provincial correctional facilities for adults in Ontario, Canada, % of N = 27.

, 2018
*OST = opioid substitution therapy, which includes opioid agonist treatments methadone and buprenorphine/naloxone.
Alexandra Patel (4856797), Lori Kiefer (3157992), Matthew J. To (504576), Leonora Regenstreif (4856794), Fiona G. Kouyoumdjian (489495)   +4 more
core   +1 more source

Factors associated with readmission to residential treatment among clients transitioned from detoxification services in Alberta, Canada

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Readmission to residential treatment increases healthcare costs, strains publicly funded systems, and may not adequately meet clients' needs. This study examined rates and predictors of readmission to residential treatment among clients transitioned from detoxification services.
Abreham Mekonnen
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Transition from methadone to subcutaneous buprenorphine depot in patients with opioid use disorder - a case report

European Psychiatry
Introduction Opioid dependence is a complex condition that often requires long-term treatment and care. Methadone, a synthetic full opioid agonist, and buprenorphine, a partial agonist at the opioid receptor, are most commonly used for substitution ...
M. Delic
doaj   +1 more source

Nociceptin/orphanin FQ – NOP receptor system: novel genetic and pharmacological tools

, 2012
The neuropeptide nociceptin/orphanin FQ (N/OFQ) selectively binds and activates the N/OFQ peptide (NOP) receptor. In cells expressing the NOP receptor N/OFQ inhibits cAMP accumulation and Ca2+ conductance and stimulates K+ currents.
Molinari, Stefano
core  

Peri‐operative management of diabetes mellitus: a multidisciplinary consensus statement from the Association of Anaesthetists and the Joint British Diabetes Societies for Inpatient Care group

Anaesthesia, EarlyView.
Summary Introduction Surgery in patients with diabetes mellitus is associated with increased morbidity and mortality compared with those who do not have diabetes mellitus. This is likely multifactorial and could be attributed to organisational issues; dysglycaemia; hospital‐acquired diabetic ketoacidosis; errors with insulin prescribing and ...
Nicholas A. Levy, Kariem El‐Boghdadly, Dileep N. Lobo, Daniel J. Stubbs, Parizad Avari, Donal Buggy, Claire Frank, Kim Howson, Jinty Moffett, Emma Morris, Omar G. Mustafa, Glynn Nash, Pádraig Ó Scanaill, Sarah Procter, Gerry Rayman, Kim Russon, Caroline Thomas, Sarah Tinsley, Allan Xu, Ketan Dhatariya   +19 more
wiley   +1 more source

NOCICEPTIN/ORPHANIN FQ RECEPTOR LIGANDS: PHARMACOLOGICAL STUDIES

, 2009
The neuropeptide nociceptin/orphanin FQ (N/OFQ) selectively binds and activates the N/OFQ peptide (NOP) receptor. At cellular level N/OFQ inhibits cAMP accumulation and Ca2+ conductance and stimulates K+ currents.
Fischetti, Carmela, Carmela Fischetti (7591079)   +1 more
core  

Critical care delirium: prevention, identification and management: a narrative review

Anaesthesia, EarlyView.
Summary Introduction Delirium is a frequent complication of critical illness and remains an important cause of short‐ and long‐term morbidity for patients admitted to ICUs. Delirium is associated with prolonged mechanical ventilation; extended ICU and hospital stay; and longer‐term health issues. Development is associated with patient (e.g.
Stephanie Kieswick, Ben Gibbison
wiley   +1 more source

Beyond the Epidural: Reframing Analgesia for the Modern Oesophagectomy

ANZ Journal of Surgery, EarlyView.
A novel analgesic framework for minimally invasive oesophagectomy to facilitate functional recovery.
William Thomas Birkett, Geraldine Ooi, Bethany White, Hamish Shilton, Liang Low, Paul Cashin, Walston Reginald Martis   +6 more
wiley   +1 more source

Improving hospital-based opioid substitution therapy (iHOST): protocol for a mixed-methods evaluation [version 2; peer review: 2 approved]

NIHR Open Research
Background Opioid substitution therapy (also known as ‘opioid agonist therapy’ or ‘medication treatment of opioid use disorder’) is associated with improved health and social outcomes for people who use heroin and other illicit opioids.
Marisha Wickremsinhe, Dan Lewer, Adam Burns, Michael Brown, Rosalind Gittins, Niamh Eastwood, Vivian Hope, Adam Holland, Penny Lewthwaite, Aubrey Ko, Adrian Noctor, Ann-Marie Morris, Jenny Scott, Andrew Preston, Sedona Sweeney, Erica Smith, Magdalena Harris, Nerissa Tilouche   +17 more
doaj   +1 more source