Results 101 to 110 of about 302,501 (282)

The opportunity to save a life: A qualitative study of a point-of-care overdose education and naloxone distribution intervention.

PLoS ONE
Canada's opioid crisis continues to escalate. Naloxone can effectively reverse the effects of opioid overdose. We planned a randomized trial on the effectiveness of a point-of-care overdose education and naloxone distribution (OEND) intervention on ...
Janet A Parsons, Benjamin Markowitz, Rekha Thomas, Kris Norris, Mercy Charles, Chantelle King, Kate Sellen, Douglas M Campbell, Pamela Leece, Michelle Klaiman, Leigh Chapman, Shaun Hopkins, Rita Shahin, Curtis Handford, Vicky Stergiopoulos, Laurie J Morrison, Carol Strike, Aaron M Orkin, SOONER investigators   +18 more
doaj   +1 more source

What anabolic–androgenic steroids reveal about the limits of current harm reduction models

Addiction, EarlyView.
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski, Jason M. Nagata, Suzanne Nielsen   +2 more
wiley   +1 more source

Drug sellers' use of a drug checking service amid the overdose crisis in British Columbia, Canada

Addiction, EarlyView.
Abstract Aims This study examined the use of a drug checking service by drug sellers in British Columbia, Canada, to assess motivations for service use and substances intended for distribution, focusing on risks associated with an unstable illicit drug market.
Pablo Gonzalez‐Nieto, Bruce Wallace, Collin Kielty, Irene Shkolnikov, Ava Margolese, Jaime Arredondo Sanchez Lira, Chris Gill, Dennis Hore   +7 more
wiley   +1 more source

‘Emptiness filled with love’: A reflexive thematic analysis of chemsex trajectories among gay, bisexual and other men who have sex with men in Almaty, Kazakhstan, using a life course framework

Addiction, EarlyView.
Abstract Background and aims The intentional use of psychoactive substances to enhance sexual experiences, known as chemsex, is associated with human immunodeficiency virus (HIV) transmission, psychological distress and social isolation among gay, bisexual and other men who have sex with men (GBMSM).
Nikolay Lunchenkov, Nadezhda Cherchenko, Elena German, Susanna Rinne‐Wolf   +3 more
wiley   +1 more source

[Opioid overdose].

Medicina (Kaunas, Lithuania), 2003
The dangers of opioid overdose have been recognized for as long as the use of opium itself. When used correctly for medical purposes, opioids are remarkably safe and effective agents. However, excessive dosing, whether with therapeutic, suicidal, or euphoric intent, may results in significant toxicity.
Dagmara, Reingardiene, Jolita, Vilcinskaite   +1 more
openaire   +1 more source

Patient Preference for Pain Medication in the Emergency Department Is Associated with Non-fatal Overdose History

Western Journal of Emergency Medicine, 2018
Introduction: Opioid overdose is a major public health problem. Emergency physicians need information to better assess a patient’s risk for overdose or opioid-related harms.
Lauren K. Whiteside, Jason Goldstick, Aaron Dora-Laskey, Laura Thomas, Maureen Walton, Rebecca Cunningham, Amy S.B. Bohnert   +6 more
doaj   +1 more source

Context, mechanisms and outcomes of a social enterprise model of residential rehabilitation for problem substance use: A realist‐informed process evaluation

Addiction, EarlyView.
Abstract Background and aims This study evaluated a three‐year residential rehabilitation programme, which aimed to support recovery from problem substance use via peer support and social enterprise activities. The aims were to clarify programme mechanisms and identify contextual factors associated with variation in outcomes.
Martin Anderson, Lucy Pickering, Mark McCann   +2 more
wiley   +1 more source

Charting the decline of the fourth wave: US overdose deaths by race, ethnicity and substance involvement

Addiction, EarlyView.
Abstract Aims To characterize decreases in overdose death rates in the United States (US) between 2023 and 2024 by race/ethnicity, and substance involvement. Design Population‐based study of national death records accessed via the Centers for Disease Control and Prevention (CDC) Wide‐ranging ONline Data for Epidemiologic Research (WONDER) platform ...
Joseph R. Friedman, Joseph J. Palamar, Daniel Ciccarone, Tommi L. Gaines, Annick Borquez, Chelsea L. Shover, Steffanie A. Strathdee   +6 more
wiley   +1 more source

Opioid Education and Nasal Naloxone Rescue Kits in the Emergency Department

Western Journal of Emergency Medicine, 2015
Introduction: Emergency departments (EDs) may be high-yield venues to address opioid deaths with education on both overdose prevention and appropriate actions in a witnessed overdose.
Dwyer, Kristin , Walley, Alexander Y. , Langlois, Breanne K. , Mitchell, Patricia M. , Nelson, Kerrie P. , Cromwell, John, Bernstein, Edward   +6 more
doaj   +1 more source

The association between naloxone distribution, buprenorphine treatment and retention and incident high‐risk opioid prescribing with opioid overdose death in Kentucky, Massachusetts, New York and Ohio, United States: An exploratory community‐level cohort study of data from the HEALing Communities Study

Addiction, EarlyView.
Abstract Aim We evaluated whether community‐level naloxone distribution, medication for opioid use disorder treatment and retention and incident high‐risk opioid prescribing rates were associated with opioid overdose death rates. Design Observational cohort conducted using 2019 to 2023 community‐level data as an exploratory analysis of the HEALing ...
Alexander Y. Walley, Debbie M. Cheng, Nathan Vandergrift, Marc Larochelle, JaNae Holloway, Jennifer L. Brown, Redonna Chandler, Laura C. Fanucchi, Daniel J. Feaster, Patricia R. Freeman, Timothy Hunt, Michelle R. Lofwall, Hannah K. Knudsen, Edward V. Nunes, Emmanuel Oga, Douglas R. Oyler, Jeffrey H. Samet, Jennifer Villani, Sharon L. Walsh, T. John Winhusen   +19 more
wiley   +1 more source