Results 201 to 210 of about 156,077 (286)

Risk of opioid overdose during buprenorphine treatment for opioid use disorder in the fentanyl era. [PDF]

Addict Behav
Chambers LC, Hallowell BD, Zullo AR, Rodriguez M, Khan MA, Berk J, Gaither R, Daly M, Wightman RS, Beaudoin FL.   +9 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, Volume 81, Issue 9, Page 3039-3070, September 2026.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter, Ian M. Adcock, Cristina Benito‐Villalvilla, Rodolfo Bianchini, Leif Bjermer, Gaetano Caramori, Luigi Cari, Kian Fan Chung, Zuzana Diamant, Ibon Eguiluz‐Gracia, Edward F. Knol, Milos Jesenak, Francesca Levi‐Schaffer, Giuseppe Nocentini, Liam O'Mahony, Oscar Palomares, Frank Redegeld, Milena Sokolowska, Betty Van Esch, Marco Zurlo, Cristiana Stellato   +20 more
wiley   +1 more source

Clinical factors linked to xylazine exposure in emergency department patients with illicit opioid overdose. [PDF]

Addiction
Love JS, Vargas-Torres C, Aldy K, Brent J, Wax P, Culbreth R, Krotulski A, Campleman S, Logan B, Abston S, Li S, Manini AF, Fentalog Study Group.   +12 more
europepmc   +1 more source

Technology‐Driven Decision Support for Opioid Tapering: A Scoping Review

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Background General practitioners manage most opioid tapering. This process requires time‐consuming, individualised planning accounting for patient preferences, dose options and costs. Consequently, clinicians need tools to support tapering.
Laurits Valberg Hemmingsen, Lærke Karner Overgaard, Uffe Kock Wiil, Daniel Pilsgaard Henriksen   +3 more
wiley   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

Paraspinal Compartment Syndrome Associated with Opioid Overdose: A Case Report. [PDF]

Clin Pract Cases Emerg Med
Habiyaremye T, Holz K, Jackson JR.
europepmc   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, Volume 183, Issue 18, Page 5458-5475, September 2026.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

Addressing opioid overdose in correctional settings needs careful consideration. [PDF]

CMAJ
Regenstreif LJ.
europepmc   +1 more source

New persistent opioid use after colorectal surgery in Sweden: A nationwide register‐based cohort study

Colorectal Disease, Volume 28, Issue 9, September 2026.
Abstract Aim To determine the incidence of new persistent opioid use (NPOU) after elective colorectal surgery in Sweden and to identify associated patient‐, procedure‐ and hospital‐level factors. Method This nationwide retrospective cohort study linked data from Swedish national health registries and included adults undergoing elective inpatient ...
Claes Gedda, Jonas Nygren, Erik Sturegård, Yunzhang Wang, Anders Thorell, Mattias Soop   +5 more
wiley   +1 more source

Cost-effectiveness of community-based interventions for reducing opioid overdose and non-overdose deaths: simulation modeling of HEALing Communities Study. [PDF]

Lancet Reg Health Am
Chhatwal J, Sahinkoc M, Chen Q, Dowd W, Xiao J, Zarkin GA, Aldridge A, Barocas JA, Cerdá M, Fareed N, Frazier LA, Hyder A, Keyes KM, Knott CE, LaRochelle M, Linas BP, Oga E, Roberts SM, Samet JH, Schackman BR, Seiber EE, Starbird LE, Villani J, Knudsen AB, Barbosa C.   +24 more
europepmc   +1 more source