Results 101 to 110 of about 59,621 (299)
Neuroimmune Interaction in the Regulation of Peripheral Opioid-mediated Analgesia in Inflammation
Frontiers in Immunology, 2016 Peripheral immune-cell-mediated analgesia in inflammation is an important endogenous mechanism of pain control. Opioid receptors localized on peripheral sensory nerve terminals are activated by endogenous opioid peptides released from immune cells to ...
Susan Hua
doaj +1 more source
Double labelling immunohistochemical characterization of autonomic sympathetic neurons innervating the sow retractor clitoridis muscle [PDF]
, 2008 Retrograde neuronal tracing and immunohistochemical methods were used to define the neurochemical content of sympathetic neurons projecting to the sow retractor clitoridis muscle (RCM). Differently from the other smooth muscles of genital organs, the RCM
Acone, Franca +6 more
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Veterinary Record, EarlyView.Background This study measured serum biomarkers at baseline and during an ovariohysterectomy in healthy female Spanish greyhounds, aiming to enhance the objectivity of current methods for assessing acute postoperative pain in dogs. Methods Blood samples from 20 Spanish greyhounds were collected before drug administration (T0‐baseline).
Rocio Navarrete‐Calvo +8 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro +14 more
wiley +1 more source
Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]
, 2004 Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core
Regulation of Opioid Receptor Trafficking and Signaling by Opioid Peptides
, 2021 Jennifer M. Kunselman
openalex +2 more sources
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Nociceptin/Orphanin FQ Opioid Peptide-Receptor Expression in the Endometriosis-Associated Nerve Fibers-Possible Treatment Option? [PDF]
Cells, 2023 Guan Q +6 more
europepmc +1 more source
Molecular Aspect of Annelid Neuroendocrine system
, 2007 Hormonal processes along with enzymatic processing similar to that found in vertebrates occur in annelids. Amino acid sequence determination of annelids precursor gene products reveals the presence of the respective peptides that exhibit high sequence ...
Salzet, M.
core +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Riluzole, approved for amyotrophic lateral sclerosis (ALS), has a glutamate‐modulating profile favourable for mitigating opioid addiction. It reduces neuronal glutamate release and enhances glutamate reuptake, offering advantages over agents that only increase glutamate reuptake.
Ewa Galaj +7 more
wiley +1 more source