N,N‐diallyl‐tyrosyl substitution confers antagonist properties on the κ‐selective opioid peptide [D‐Pro10]dynorphin A(1–11) [PDF]
Jean Edouard Gairin +5 more
openalex +1 more source
Food and the brain: Neural and endocrine control of feeding, metabolism, and reproduction
Abstract Feeding and reproductive function are regulated by intricate systems that monitor food availability and energy stores, and on the basis of energy status, promote or put a brake on reproduction. This is particularly evident in the systems that regulate feeding and reproductive state in female mammals.
Naira da Silva Mansano +2 more
wiley +1 more source
Insights into the interaction between hemorphins and δ-opioid receptor from molecular modeling
Hemorphins are short atypical opioid peptide fragments embedded in the β-chain of hemoglobin. They have received considerable attention recently due to their interaction with opioid receptors.
Priya Antony +4 more
doaj +1 more source
Monoclonal antibody to the message sequence Tyr-Gly-Gly-Phe of opioid peptides exhibits the specificity requirements of mammalian opioid receptors. [PDF]
T Meo +6 more
openalex +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth +5 more
wiley +1 more source
Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso +5 more
wiley +1 more source
The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin +6 more
wiley +1 more source
Delta Opioid Receptor Activation with Delta Opioid Peptide [d-Ala2, d-Leu5] Enkephalin Contributes to Synaptic Improvement in Rat Hippocampus against Global Ischemia. [PDF]
Zhang G +10 more
europepmc +1 more source
Evidence for a Dual Mechanism in the Anesthetic Action of an Opioid Peptide [PDF]
Barbara A. Dodson, Keith W. Miller
openalex +1 more source
Pain Phenotype in Knee Osteoarthritis: Implications for Mechanism‐Based Therapy
The paper reported on the precise and individual treatment of knee osteoarthritis (KOA) pain based on its new classification, including Nociceptive Pain, Neuropathic Pain, and Nociplastic Pain. Tailored treatment recommendations for different types of pain through exploring potential mechanisms of pain in KOA are provided to achieve better clinical ...
Chenchang He +5 more
wiley +1 more source

