Evaluation of in silico approach for prediction of presence of opioid peptides in wheat
Opioid like morphine and codeine are used for the management of pain, but are associated with serious side-effects limiting their use. Wheat gluten proteins were assessed for the presence of opioid peptides on the basis of tyrosine and proline within ...
Swati Garg+3 more
doaj
Insights into the interaction between hemorphins and δ-opioid receptor from molecular modeling
Hemorphins are short atypical opioid peptide fragments embedded in the β-chain of hemoglobin. They have received considerable attention recently due to their interaction with opioid receptors.
Priya Antony+4 more
doaj +1 more source
Lack of effect of the nociceptin opioid peptide agonist Ro 64-6198 on pain-depressed behavior and heroin choice in rats. [PDF]
Moerke MJ, Negus SS, Banks ML.
europepmc +1 more source
Anatomical relationship between opioid peptides and receptors in rhesus monkey brain [PDF]
Michael E. Lewis+3 more
openalex +1 more source
Threonine 180 Is Required for G-protein-coupled Receptor Kinase 3- and β-Arrestin 2-mediated Desensitization of the µ-Opioid Receptor in Xenopus Oocytes [PDF]
To determine the sites in the µ-opioid receptor (MOR) critical for agonist-dependent desensitization, we constructed and coexpressed MORs lacking potential phosphorylation sites along with G-protein activated inwardly rectifying potassium channels ...
Celvert, Jeremy P.+4 more
core
Dreaming of Better Treatments: Advances in Drug Development for Sleep Medicine and Chronotherapy
ABSTRACT Throughout history, the development of new sleep medicines has been driven by progress in our understanding of the mechanisms underlying sleep. Ancient civilisations used their understanding of the sedative nature of natural herbs and compounds to induce sleep.
Brooke A. Prakash+5 more
wiley +1 more source
N,N‐diallyl‐tyrosyl substitution confers antagonist properties on the κ‐selective opioid peptide [D‐Pro10]dynorphin A(1–11) [PDF]
Jean Edouard Gairin+5 more
openalex +1 more source
Abstract Background Cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS) are both characterized by episodic, acute transitions from asymptomatic states to highly symptomatic states of nausea, repetitive vomiting, and often severe abdominal pain.
David J. Levinthal+2 more
wiley +1 more source
Monoclonal antibody to the message sequence Tyr-Gly-Gly-Phe of opioid peptides exhibits the specificity requirements of mammalian opioid receptors. [PDF]
T Meo+6 more
openalex +1 more source
Neuro-physiological characterization of opioid peptide actions on neurohumoral transmission in the mammalian central nervous system [PDF]
Mercuri, Nicola+4 more
core +1 more source