Results 151 to 160 of about 52,140 (266)

Neuro-physiological characterization of opioid peptide actions on neurohumoral transmission in the mammalian central nervous system [PDF]

open access: yes, 1986
Mercuri, Nicola   +4 more
core   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
HS treatment algorithm. Abstract Introduction This second part of the S2k guidelines is an update of the 2015 S1 European guidelines. Objective These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS ...
C. C. Zouboulis   +36 more
wiley   +1 more source

Targeting pain and inflammation by peripherally acting opioids

open access: yesFrontiers in Pharmacology, 2013
Christoph eStein
doaj   +1 more source

Investigating the importance of social vulnerability in opioid-related mortality across the United States [PDF]

open access: yesarXiv
The opioid crisis remains a critical public health challenge in the United States. Despite national efforts to reduce opioid prescribing rates by nearly 45\% between 2011 and 2021, opioid overdose deaths more than tripled during this same period. This alarming trend reflects a major shift in the crisis, with illegal opioids now driving the majority of ...
arxiv  

Common genetic variants do not impact clinical prediction of methotrexate treatment outcomes in early rheumatoid arthritis

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Background Methotrexate (MTX) is the mainstay initial treatment of rheumatoid arthritis (RA), but individual response varies and remains difficult to predict. The role of genetics remains unclear, but studies suggest its importance. Methods Incident RA patients starting MTX‐monotherapy were identified through a large‐scale Swedish register ...
Anton Öberg Sysojev   +10 more
wiley   +1 more source

N,N‐diallyl‐tyrosyl substitution confers antagonist properties on the κ‐selective opioid peptide [D‐Pro10]dynorphin A(1–11) [PDF]

open access: green, 1988
Jean Edouard Gairin   +5 more
openalex   +1 more source

Enteric neuropathy and the vagus nerve: Therapeutic implications

open access: yesNeurogastroenterology &Motility, EarlyView.
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley   +1 more source

Opioid peptides derived from food proteins. The exorphins

open access: hybrid, 1979
C. Zioudrou   +2 more
openalex   +1 more source

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